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View Structure Prediction Details

Protein: nuo-1
Organism: Caenorhabditis elegans
Length: 479 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nuo-1.

Description E-value Query
Range
Subject
Range
gi|157751214 - gi|157751214|ref|XP_001679319.1| Hypothetical protein CBG02970 [Caenorhabditis briggsae AF16]
gi|187036977, gi... - gi|39597344|emb|CAE59572.1| Hypothetical protein CBG02970 [Caenorhabditis briggsae], gi|187036977|em...
630.0 [0..1] [479..1]

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Predicted Domain #1
Region A:
Residues: [1-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASAAVSLGA RLIGQNVPKV AVRGVVTSAQ NANAQVKQEK TSFGNLKDSD RIFTNLYGRH  60
   61 DYRLKGAMAR GDWHKTKEII LKGSDWILGE LKTSGLRGRG GAGFPSGMKW GFMNKPFDGR 120
  121 PKYLVVNADE GEPGTCKDRE IMRHDPHKLI EGCLIGGVAM GARAAYIYIR GEFYNEACIL 180
  181 QEAINEAYKA GYLGKDCLGT GYNFDVFVHR GAGAYICGEE TALIESLEGK QGKPRLKPPF 240
  241 PADIGLFGCP TTVTNVETVA VAPTICRRGG DWFASFGRER NRGTKLFCIS GQVNNPCTVE 300
  301 EEMSVPLKDL IERHCGGVIG GWDNLLAIIP GGSSVPLMPK NVCDTVLMDF DALVAAQSGL 360
  361 GTAAVIVMNK QTDIVKCIAR LSLFYKHESC GQCTPCREGC NWLNKMMWRF VDGKAKPSEI 420
  421 DMMWELSKQI EGHTICALGD AAAWPVQGLI RHFRPELERR MAEFHKQVLA EQGAKQISQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 150.0
Match: 2fug1
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADH dehydrogenase activity 13.4136491947011 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 12.443012098477 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 12.1743193111446 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 11.5132141901667 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 10.8948060301507 bayes_pls_golite062009
oxidoreductase activity 6.75377893144873 bayes_pls_golite062009
formate dehydrogenase activity 3.21486196088149 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 2.15499718507114 bayes_pls_golite062009
electron carrier activity 1.50427278540084 bayes_pls_golite062009
catalytic activity 1.46362311772849 bayes_pls_golite062009
iron-sulfur cluster binding 1.25645944988955 bayes_pls_golite062009
metal cluster binding 1.25645944988955 bayes_pls_golite062009
binding 1.25265721111105 bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor 0.530794334701446 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.471058486160512 bayes_pls_golite062009
ferredoxin hydrogenase activity 0.281674499766589 bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor 0.281674499766589 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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