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View Structure Prediction Details

Protein: rpy-1
Organism: Caenorhabditis elegans
Length: 596 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpy-1.

Description E-value Query
Range
Subject
Range
gi|113476999, gi... - gi|113476999|ref|YP_723060.1| peptidase-like [Trichodesmium erythraeum IMS101], gi|110168047|gb|ABG5...
274.0 [0..2] [549..202]

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Predicted Domain #1
Region A:
Residues: [1-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQRQAKQHM QAGVKLYHQR HYAQAINKWR QSLNRLNNAE DRFITLGYLA QALCDQGEYE  60
   61 GMLSYALSQM QLATDQNDSA MKCEAFLNLA KAYERLADFT KALQYGKASL EHPSMDPRTP 120
  121 GYAHLTIALA HLGMSQFQQC LESFESAMNV ANETSDRLLE LQICVGLGSL FTLLRDITKA 180
  181 LIFLRNALAI VQSVTVDDVH AKYRCLILYH LSVALRMKGS LVDAKEACDE ASQLAVEMGN 240
  241 RAIHARCMCS LADIYRELGE SEAKETITKS WARYEDAYRV MRGANDKMGE VLVLSSMAKS 300
  301 ASESRSHYTG QCECQAIQLN KKCIEIANQI GCKHVVLKCH LRLAELYSQL NDDDSEETAR 360
  361 RAASRLTQEM QLFCNFCGQR YGLKDESLQA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.06634498978728 bayes_pls_golite062009
protein binding 1.60857679122674 bayes_pls_golite062009
signal transducer activity 0.945586902460441 bayes_pls_golite062009
molecular transducer activity 0.945586902460441 bayes_pls_golite062009
receptor activity 0.273696548489824 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [391-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRCSHIFHEK CLHTYLLQRT DQTCPKCRCR AVLSDNISIR SSIASTIDVQ SPSTSFAPPG  60
   61 GVATPLVSAA AELGDITPQA TLTRRSQQDK ILRGAEKDID RVDRSLARLK SQQSAAANAC 120
  121 SAVAVPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1zbpA
Description: Crystal Structure of the Hypothetical protein VPA1032 from Vibrio parahaemolyticus, Northeast Structural Genomics Target VpR44
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [518-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEVPSTTASC ASEPILTAST TSQSHTHSNA NHKPPPPPRK PCCSQAALPP SSIVALPPAM  60
   61 PLAEDGPLVI THTPTVTDV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle