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View Structure Prediction Details

Protein: cah-1
Organism: Caenorhabditis elegans
Length: 365 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cah-1.

Description E-value Query
Range
Subject
Range
gi|114663050 - gi|114663050|ref|XP_001143159.1| PREDICTED: similar to carbonic anhydrase VII [Pan troglodytes]
307.0 [0..98] [358..47]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFECSHFPL FLIILTCHIS PLKSSQNYQW SYDSDVFGGP HFWGLVEKDW WMCKKGRLQS  60
   61 PIDIQPDRLL FDASVKPVSY AELNF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.38
Match: 1zncA
Description: Carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [86-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLIIYLTISL KLMRYIFTCA HLFACNKKLG TWNRIFGANI AKFRAWVVYI IIFHAQVPQL  60
   61 QVVSEFVNTG QMVRVRIGYS SKKPSVNITS GPLYGYRYRV QRIDFHMGRK NENGSEHTIN 120
  121 GRRFPMEVQL VAYNTDLYPN FTSASKSPHG IAILSVLVDF GPETNQELIK LTIATASISY 180
  181 KDQRVQLADF EPWRLLPFTR DIITYEGSLT SPGCHETVTW IILNQPIFIK KEHFEEWSHL 240
  241 YLSMEGAEKV PVAPNFRKIQ ETNNRLVRTN IQHKVWIFLS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.69897
Match: 1ugfA
Description: HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.243080801473815 bayes_pls_golite062009
catalytic activity 0.072358783043549 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle