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View Structure Prediction Details

Protein: CE01112
Organism: Caenorhabditis elegans
Length: 522 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE01112.

Description E-value Query
Range
Subject
Range
CE33750 - Calcitonin receptor family status:Partially_confirmed UniProt:P30650 protein_id:CAA77471.2
338.0 [0..1] [453..1]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSISTAGA VVDDFQMSCR FSNFGDHAPE SFDSLSCGAC FYFIFMLVEH YKDRYVASLC  60
   61 EDTFGVLVCP VDVSDKICNC YNREYVYNIP EFALNSSRIK PLNHLRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPPLPFQFDL IVKDCCSAAR YCCRNTLVKY HHRVDDSPCP PTWDGWNCFD SATPGVVFKQ  60
   61 CPNYIYGGSN IKTDYDRLSQ KVCRSNGWAT PE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 2jodA
Description: No description for 2jodA was found.

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 7.11838006478957 bayes_pls_golite062009
transmembrane receptor activity 5.41031049482732 bayes_pls_golite062009
receptor activity 5.12318570081263 bayes_pls_golite062009
signal transducer activity 4.16951678107564 bayes_pls_golite062009
molecular transducer activity 4.16951678107564 bayes_pls_golite062009
pituitary adenylate cyclase-activating polypeptide receptor activity 2.36627671354861 bayes_pls_golite062009
binding 1.90935265027969 bayes_pls_golite062009
peptide binding 1.37672683415634 bayes_pls_golite062009
growth hormone-releasing hormone receptor activity 0.621179725102141 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [200-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNAAAREHTD YTGCMSNGDV EARILAGLLT YSASVIFLIP AVFLLTLLRP IRCQPMFILH  60
   61 RHLLISCLLY GAFYLITVSL FVVNDAPLSS QVFQNHLFCR LLFSIQLRYL RLTNFTWMLA 120
  121 EAVYLWRLLH TAQHSEGETL RSYKVICWGV PGVITVVYIF VRSLNDDVGM CWIENSTVAW 180
  181 IEWMIITPSL LAMGVNLLLL GLIVYILVKK LRCDPHLERI QYRKAVRGAL MLIPVFGVQQ 240
  241 LLTIYRFSNT YYQVTDQSLN GLQGMFVSFI VCYTNRSVVE CVLKFWSSHQ EKRALGAECR 300
  301 QRMSIQESGK LILRPPQTEH VVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle