YRC Public Data Repository - Protein Structure Prediction

Protein:	CE00832
Organism:	Caenorhabditis elegans
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE00832.

Description	E-value	Query Range	Subject Range
gi\|157777422 - gi\|157777422\|ref\|XP_001666777.1\| hypothetical protein CBG24154 [Caenorhabditis briggsae AF16] gi\|187040443, gi... - gi\|39579869\|emb\|CAE56449.1\| Hypothetical protein CBG24154 [Caenorhabditis briggsae], gi\|187040443\|em...	176.0	[0..1]	[212..1]
NDS8A_ARATH - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-A, mitochondrial OS=Arabidopsis thaliana GN=At...	156.0	[0..44]	[212..54]
NDUS8_MACFA - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Macaca fascicularis GN=NDUFS... gi\|109105179 - gi\|109105179\|ref\|XP_001104103.1\| PREDICTED: NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (N...	153.0	[0..9]	[212..4]
gi\|109463301, gi... - gi\|27661165\|ref\|XP_215197.1\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) Fe-S protein 8 [R...	153.0	[0..9]	[212..4]
gi\|77416915 - gi\|77416915\|gb\|ABA81853.1\| NADH:ubiquinone oxidoreductase-like [Solanum tuberosum]	152.0	[0..44]	[212..61]
gi\|66773136, gi\|... - gi\|66773136\|ref\|NP_001019573.1\| hypothetical protein LOC554100 [Danio rerio], gi\|66267262\|gb\|AAH9511...	152.0	[0..15]	[212..12]
gi\|68464733, gi\|... - gi\|68465112\|ref\|XP_723255.1\| potential mitochondrial Complex I, NUIM_23kd subunit [Candida albicans ... orf19.4758, orf1... - orf19.4758 CGDID:CAL0004489 Assembly 19, Contig19-10215 (79377, 80117) CDS, translated using codon t...	151.0	[0..43]	[212..77]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMKSVAVLT KGMFGRIPAQ LAVSSVPSNT IQKRSNYKFV GMPNETDGTL AGDLNYGLHN  60
   61 VFFTELFRGF GVMLGHVFME PATINYPFEK GPLSSRFRGE HALRRYPSGE ERCIACKLCE 120
  121 AICPAQAITI EAETRPDGSR RTTRYDIDMT KCIYCGLCQE ACPVDAIVEG PNFEYSTETH 180
  181 EELLYNKEKL LLNGDRWEPE LASNLQAEYL YR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.69897
Match:	2fug9
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	12.5726198200461	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	11.5379710261128	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	11.4267068380664	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	10.7661444048967	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	10.0573871968611	bayes_pls_golite062009
oxidoreductase activity	5.95698221294919	bayes_pls_golite062009
electron carrier activity	5.42600867641421	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	4.00434209032307	bayes_pls_golite062009
iron-sulfur cluster binding	3.32581564966388	bayes_pls_golite062009
metal cluster binding	3.32581564966388	bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity	3.29174700910768	bayes_pls_golite062009
formate dehydrogenase activity	2.79579164562277	bayes_pls_golite062009
binding	0.850925220183928	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009
protein binding	0.122045589752402	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	0.115812441015069	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0827182678048914	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: