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View Structure Prediction Details

Protein: ent1
Organism: Schizosaccharomyces pombe
Length: 706 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ent1.

Description E-value Query
Range
Subject
Range
gi|111307118 - gi|111307118|gb|AAI20215.1| EPN2 protein [Bos taurus]
341.0 [0..3] [274..1]
gi|49903949, gi|... - gi|50300479|ref|NP_001002022.1| enthoprotin [Rattus norvegicus], gi|49903949|gb|AAH76397.1| Enthopro...
338.0 [0..5] [470..7]
gi|26006105 - gi|26006105|dbj|BAC41396.1| mKIAA0171 protein [Mus musculus]
332.0 [0..7] [470..28]
gi|83405958 - gi|83405958|gb|AAI10606.1| EPN3 protein [Homo sapiens]
326.0 [0..3] [309..1]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFSALAYNL LAKNFSKGYT DTQIKVRNAT TNDSWGPSGT AMAEIAELTY DQNEMLEVMD  60
   61 IIDRRLNDKG KNWRHVFKSL SLLEYCLHNG SENVVRWAKD NIYIITTLRE FVYVDDNGHD 120
  121 QGQNVRTKAK EITSLLEDEH ALKEARGDSR ERDRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.39794
Match: 1h0aA
Description: Epsin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.70535896247543 bayes_pls_golite062009
binding 2.34501465852339 bayes_pls_golite062009
protein binding 1.97365365208963 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.20269437433936 bayes_pls_golite062009
phosphoinositide binding 0.87586037360588 bayes_pls_golite062009
phospholipid binding 0.84481265656013 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009
GTPase binding 0.0887270623721197 bayes_pls_golite062009
small GTPase binding 0.0268749201897704 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRTRSSRFD DDDDDRAPYE ESRLSRAPSR ASRYDDDDRD HRSRRRSRSR RPGRSRSRRR  60
   61 SRRPSPSAEH NSAEENDPEL QRVIEESKRQ AEEDAKRRNM ANDSEAELQK AIQLSKEEDE 120
  121 ARQRH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.31
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [281-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QREREQQEQA FMGNQQNAYQ PVDFFGNPVQ PQPTGFLQQQ PTGFIRPQNT GFVQPQYTGF  60
   61 VQPQHTGFVQ PQATGF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 19.356547
Match: PF08226.2
Description: No description for PF08226.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [357-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPQRTGFVQ PQATGFVQPQ ATGFVQPQAT GFMQPQRTGF VQPQATGFMQ PQRTGFVQPQ  60
   61 ATGFMQPQRT GFVQPQATGF IQPQRTGFVQ PQQNGFFNPQ PTGYMQPQRT GMMQPQRTGF 120
  121 SQPFESNNPF PVMQPQRTGF GQTPNAPMMA PNHTGYVHPQ PTGLQRQTTG YTGNNNPYSR 180
  181 PLQSQSTGIL QQQQQQSAPR L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [558-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPTKTGSNNP FAQFSNLPSQ STAPATKPMK PVRTGDDRFS NIAQAISTGN PMGTDSFGNI  60
   61 GLTRVPTQHT GSKFTNSAGQ TIQAQATGNT HNPFQSQQAT GYYKQPMQQQ QNMQQPYYNQ 120
  121 QNYNYQNQQP MQGMQQQSMQ PQVGSLIDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle