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View Structure Prediction Details

Protein: rga7
Organism: Schizosaccharomyces pombe
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rga7.

Description E-value Query
Range
Subject
Range
gi|28926506, gi|... - gi|32408503|ref|XP_324733.1| hypothetical protein [Neurospora crassa], gi|28926506|gb|EAA35478.1| hy...
gi|85114553 - gi|85114553|ref|XP_964714.1| hypothetical protein NCU00553 [Neurospora crassa OR74A]
283.0 [0..35] [695..42]
gi|42549823, gi|... - gi|46128521|ref|XP_388814.1| hypothetical protein FG08638.1 [Gibberella zeae PH-1], gi|42549823|gb|E...
282.0 [0..34] [695..78]
gi|2583215 - gi|2583215|gb|AAB82943.1| GTPase activating protein homolog [Cochliobolus heterostrophus]
278.0 [0..3] [695..72]
gi|111070748 - gi|111070748|gb|EAT91868.1| hypothetical protein SNOG_00373 [Phaeosphaeria nodorum SN15]
275.0 [0..2] [695..32]
gi|109122771 - gi|109122771|ref|XP_001117237.1| PREDICTED: similar to minor histocompatibility antigen HA-1 [Macaca...
274.0 [0..5] [694..503]
gi|67537150, gi|... - gi|67537150|ref|XP_662349.1| hypothetical protein AN4745.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
274.0 [0..6] [695..26]
GMIP - GEM interacting protein
273.0 [0..1] [695..45]

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Predicted Domain #1
Region A:
Residues: [1-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSAPSSSTT PASPPTSPPN TTSSDDFAVL KEPKVEAILN SELGLAILND RIKDYLLTCK  60
   61 ELAGFFKKRS ILEEESGKNL QKLAKSYLET FQSKHHSPQS FSASVITSME IHEQLANHSL 120
  121 TLQKTLSAFS DQVIEFHKNA ERKRKSIKEY AKKQENAYLE AVMQMDKSKS RFKGAETEYN 180
  181 RALDNKNTGD SQKKVGFFKP KSNAQLTKLE DEARLKAENA ESDMHSKIEN AQNVQKQLLC 240
  241 IHRPNYIKQF FSLQREIESS LIANYLRYTK LCESNTLLNG LTIRPQKPTP TNCGLQHALD 300
  301 NINANTDFVQ YVLHASIKHE DNKNPTDASK TKIIQPPSSY GTGSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.30103
Match: 2eflA
Description: No description for 2eflA was found.

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 2.86582611923959 bayes_pls_golite062009
binding 2.43584893484993 bayes_pls_golite062009
protein binding 1.87308005875135 bayes_pls_golite062009
identical protein binding 0.909409198394921 bayes_pls_golite062009
enzyme binding 0.58709209959999 bayes_pls_golite062009
GTPase binding 0.50066793947946 bayes_pls_golite062009
GTPase regulator activity 0.459881864914566 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.456472132383968 bayes_pls_golite062009
enzyme regulator activity 0.180886944097381 bayes_pls_golite062009
small GTPase binding 0.0531578648468707 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [346-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGKTNPPVNP TIKVTAAIPS PLQNTNPAPS TFPNPSVASP AFPNSSTSNP STAPASASPL  60
   61 ASTLKPSTAN DTNGSSSSSS SNPRTSSPLA SNAENKPPVA QQSPPVLLPT LPPIQTTTIQ 120
  121 TSREVAPPPS SINSNRAASP FRPTSVSPQP SSPTKSLLFG ARLDAIILRE HSNIPNIVMQ 180
  181 CTSQVENFGL NLQGIYRVPS SSARVNMLRS QFENNPLLQL HTPEDYENDV HAVADLLKIF 240
  241 FRELREPLIP DNHQRDFIDA GNVEDESRRR DAVHRAINDL PDANYSTIRH LTIHLAKIKE 300
  301 NSDVNKMSTN NLAIIWGPTI IKQATIPEIS SFSRTIEILI DYCFTIFDYD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
Rho GTPase activator activity 4.58620967349979 bayes_pls_golite062009
Rac GTPase activator activity 4.48279904625182 bayes_pls_golite062009
actin binding 4.17357159737697 bayes_pls_golite062009
cytoskeletal protein binding 3.42802398019084 bayes_pls_golite062009
microfilament motor activity 2.96155001519594 bayes_pls_golite062009
GTPase regulator activity 2.70614727793157 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 2.68579854252375 bayes_pls_golite062009
actin filament binding 2.45667344398622 bayes_pls_golite062009
binding 2.36195429973813 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 2.06038764955701 bayes_pls_golite062009
motor activity 2.04743766323523 bayes_pls_golite062009
enzyme regulator activity 1.9750017471254 bayes_pls_golite062009
small GTPase regulator activity 1.95738547986197 bayes_pls_golite062009
actin-dependent ATPase activity 1.74529419104576 bayes_pls_golite062009
tubulin binding 1.56332747753627 bayes_pls_golite062009
protein binding 1.29100556128076 bayes_pls_golite062009
Ras GTPase activator activity 1.09070479183477 bayes_pls_golite062009
Rho guanyl-nucleotide exchange factor activity 0.967362611034944 bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity 0.958295643211986 bayes_pls_golite062009
myosin heavy chain kinase activity 0.847021935833721 bayes_pls_golite062009
GTPase activator activity 0.717730683557543 bayes_pls_golite062009
microtubule binding 0.648232426961013 bayes_pls_golite062009
diacylglycerol binding 0.61310450668925 bayes_pls_golite062009
ADP binding 0.56346827542888 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.36751853312336 bayes_pls_golite062009
transcription regulator activity 0.348246993470003 bayes_pls_golite062009
Rho GTPase binding 0.33949271618205 bayes_pls_golite062009
enzyme activator activity 0.298334474872045 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle