YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC645.10
Organism:	Schizosaccharomyces pombe
Length:	484 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC645.10.

Description	E-value	Query Range	Subject Range
gi\|50306057, gi\|... - gi\|50306057\|ref\|XP_452990.1\| unnamed protein product [Kluyveromyces lactis], gi\|49642123\|emb\|CAH0184... gi\|49642123 - gi\|49642123\|emb\|CAH01841.1\| KLLA0C17688p [Kluyveromyces lactis]	346.0	[0..3]	[482..7]
gi\|9836828 - gi\|9836828\|gb\|AAG00316.1\|AF207744_1 tRNA nucleotidyltransferase [Kluyveromyces lactis]	346.0	[0..3]	[482..7]
gi\|151944885 - gi\|151944885\|gb\|EDN63144.1\| tRNA nucleotidyltransferase [Saccharomyces cerevisiae YJM789] CCA1_YEAST - CCA tRNA nucleotidyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28... CCA1 - ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytoso... gi\|207345792 - gi\|207345792\|gb\|EDZ72498.1\| YER168Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405724 - gi\|190405724\|gb\|EDV08991.1\| tRNA nucleotidyltransferase [Saccharomyces cerevisiae RM11-1a]	341.0	[0..3]	[482..28]
CCA1_CANGA - CCA tRNA nucleotidyltransferase, mitochondrial OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM... CCA1_CANGA - tRNA nucleotidyltransferase, mitochondrial OS=Candida glabrata GN=CCA1 PE=1 SV=2	340.0	[0..1]	[482..11]
gi\|8698608 - gi\|8698608\|gb\|AAF78448.1\|AF098803_1 tRNA nucleotidyltransferase [Candida glabrata]	340.0	[0..1]	[482..11]
gi\|67900650, gi\|... - gi\|67900650\|ref\|XP_680581.1\| hypothetical protein AN7312.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	322.0	[0..3]	[477..13]
gi\|85108987 - gi\|85108987\|ref\|XP_962692.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32416500, gi\|... - gi\|39979137\|emb\|CAE85511.1\| related to tRNA nucleotidyltransferase [Neurospora crassa], gi\|32416500\|...	320.0	[0..2]	[483..67]
orf19.4705, orf1... - orf19.4705 CGDID:CAL0004347 Assembly 19, Contig19-10212 (293264, 291621) CDS, reverse complemented, ... gi\|68466285, gi\|... - gi\|68466576\|ref\|XP_722770.1\| potential tRNA CCA-pyrophosphorylase [Candida albicans SC5314], gi\|6846...	316.0	[0..5]	[482..25]
gi\|29339285, gi\|... - gi\|29347385\|ref\|NP_810888.1\| tRNA nucleotidyltransferase [Bacteroides thetaiotaomicron VPI-5482], gi...	315.0	[0..5]	[482..27]
gi\|115387873, gi... - gi\|115387873\|ref\|XP_001211442.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	314.0	[0..4]	[483..2]

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Predicted Domain #1

Region A:
Residues: [1-484]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSRIVLNDV EKKVVNLLKK TADFIESKSS SSSSLEVRLA GGWVRDKLLG LSSDDLDVTL  60
   61 NKVTGVDFAN SIFEYVHSLD SDSVIPYKDA LGKLTVNPDQ SKHLETATLS LFDLDIDFVG 120
  121 LRAESYDDKS RIPSVTPGTV ETDALRRDFT VNTLFFNIRT EKIEDITKRG YKDLQTKVLV 180
  181 TPISPLQSFL EDPLRILRGI RFASRFEFTI DPSVVSAIQD PKVCKAFEKK VSKERVGEEI 240
  241 EKMLKGANAK LALQLLYSTN TYQFTFDTLP AEKEFQIPKA LEATESLFQS LALTFPKLMK 300
  301 LSEDEKIGLW LYVALIPWSS QTVMVKKKQF YIPAIIAKDK LKLRSTYVNQ LNQCCTFNPI 360
  361 FDELVNDTST KNCSSIGSLI RQLNKSWEVV FLTSVIYSCC KTPAASVSNT FSSYKSLYDF 420
  421 IYDKNLQNAY NMKPLLDGKQ IMKNVGVKPG PQLKETMDNM ISWQFKHPEG SVEDCVAYLQ 480
  481 SLKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.522879
Match:	1ou5A
Description:	tRNA CCA-adding enzyme, C-terminal domains; tRNA CCA-adding enzyme, head domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring phosphorus-containing groups	2.63905617158862	bayes_pls_golite062009
transferase activity	2.28535908015265	bayes_pls_golite062009
nucleotidyltransferase activity	2.17198033243932	bayes_pls_golite062009
tRNA binding	1.96218336722441	bayes_pls_golite062009
RNA binding	1.77578561123536	bayes_pls_golite062009
nucleic acid binding	1.43322212500405	bayes_pls_golite062009
polynucleotide adenylyltransferase activity	1.24026612395993	bayes_pls_golite062009
tRNA nucleotidyltransferase activity	1.05100814747368	bayes_pls_golite062009
DNA binding	0.920001549206154	bayes_pls_golite062009
binding	0.888087430062829	bayes_pls_golite062009
catalytic activity	0.75232920999699	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: