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View Structure Prediction Details

Protein: SPBC18E5.02c
Organism: Schizosaccharomyces pombe
Length: 509 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC18E5.02c.

Description E-value Query
Range
Subject
Range
HEM0_OPSTA - 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Opsanus tau GN=alas2 PE=2 SV=1
300.0 [0..9] [501..78]
gi|94409483 - gi|94409483|ref|XP_985853.1| PREDICTED: similar to 5-aminolevulinate synthase, erythroid-specific, m...
293.0 [0..6] [507..385]
HEM0_DELLE - 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Delphinapterus leucas GN=ALAS2 PE=2...
291.0 [0..13] [507..59]
gi|28586 - gi|28586|emb|CAA39795.1| delta-aminolevulinate synthase (erythroid) [Homo sapiens]
290.0 [0..13] [507..59]
HEM0_BOVIN - 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Bos taurus GN=ALAS2 PE=2 SV=1
289.0 [0..13] [507..64]
gi|484671 - gi|484671|pir||JX0278 5-aminolevulinate synthase (EC 2.3.1.37) precursor, erythroid-specific, mitoch...
288.0 [0..13] [507..64]
gi|45595712 - gi|45595712|gb|AAH67149.1| Alas2 protein [Danio rerio]
288.0 [0..9] [503..86]
HEM0_PONAB - 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Pongo abelii GN=ALAS2 PE=2 SV=1
HEM0_PONPY - 5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor - Pongo pygmaeus (Orangutan)
288.0 [0..13] [507..64]

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Predicted Domain #1
Region A:
Residues: [1-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYSYPFFDD VYAYYNQTVT FFGKALDVLP GSPIVKRYIK SSYQNDPLRT FIEFLLLVFA  60
   61 AYYVLRKPRT SPDNNYVEFT EKEINELVDD WKPEPLVAEL TDVEKLELKS IPVLESVHLH 120
  121 TKLIDGRPIT NFASFNFLDL AENKHITECA VATLRECGLG ACGPPGFYGT QDKHLRLEKD 180
  181 IASFIGVERA IVYAQSFQTI SSVIPAFSKR GDILVVDEAC NFAIQKGIQI SRTTIRYFKH 240
  241 NNMKDLERIL QELEDDFVKH NRPLTRRFII TEGISENYGD MVDLTKIVAL KKKYKYRLIL 300
  301 DETWSFGTCG RTGKGLTEHF GVPPTDVEII IGSLTTSLAG GGGFCAGSEL MVEHQRLSGM 360
  361 AYIYSAALPA SLAVAAYEAI SILSRDGGSM LNDLRSKSAL FHAKLSRNKF FETSSDIESP 420
  421 IIHLRFKDKD ISHDKQVFLL EEIVELCIAE GFLIARAKRV ESLERVKVQP SLRICISTGH 480
  481 SAEEIEKLAL LIKEKTEIVF DKHKVINQV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.221849
Match: 1fc4A
Description: 2-amino-3-ketobutyrate CoA ligase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
serine C-palmitoyltransferase activity 9.1839236553858 bayes_pls_golite062009
C-palmitoyltransferase activity 9.1839236553858 bayes_pls_golite062009
C-acyltransferase activity 4.29379571948906 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity 1.60594586591965 bayes_pls_golite062009
transcription regulator activity 1.07873942461292 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 0.977426345202718 bayes_pls_golite062009
transaminase activity 0.947342543265575 bayes_pls_golite062009
DNA binding 0.886628214497634 bayes_pls_golite062009
nucleic acid binding 0.814403324199462 bayes_pls_golite062009
structural molecule activity 0.811208803619077 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
carbon-sulfur lyase activity 0.698312655247044 bayes_pls_golite062009
binding 0.661198018681765 bayes_pls_golite062009
transcription factor activity 0.615294010373048 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle