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View Structure Prediction Details

Protein: sap62
Organism: Schizosaccharomyces pombe
Length: 217 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sap62.

Description E-value Query
Range
Subject
Range
gi|195379390, gi... - gi|27374358|gb|AAO01098.1| CG10754-PA [Drosophila virilis], gi|195379390|ref|XP_002048462.1| GJ13983...
363.0 [0..1] [214..1]
gi|54640988, gi|... - gi|54640988|gb|EAL29739.1| GA10545 [Drosophila pseudoobscura pseudoobscura], gi|125979941|ref|XP_001...
gi|195166735, gi... - gi|195166735|ref|XP_002024190.1| GL22896 [Drosophila persimilis], gi|194107545|gb|EDW29588.1| GL2289...
gi|54640988|gb|E... - GA10545-PA [Drosophila pseudoobscura], GA10545 [Drosophila pseudoobscura pseudoobscura]
360.0 [0..1] [214..1]
gi|85068275 - gi|85068275|ref|XP_962153.1| hypothetical protein NCU07299 [Neurospora crassa OR74A]
gi|28923750, gi|... - gi|32414211|ref|XP_327585.1| hypothetical protein [Neurospora crassa], gi|28923750|gb|EAA32917.1| hy...
357.0 [0..1] [215..1]
SF3A2_RAT - Splicing factor 3A subunit 2 OS=Rattus norvegicus GN=Sf3a2 PE=2 SV=1
357.0 [0..1] [215..1]
gi|124000543 - gi|124000543|gb|ABM87780.1| splicing factor 3a, subunit 2, 66kDa [synthetic construct]
SF3A2 - splicing factor 3a, subunit 2, 66kDa
gi|114674504, gi... - gi|114674506|ref|XP_001150681.1| PREDICTED: splicing factor 3a, subunit 2 isoform 5 [Pan troglodytes...
357.0 [0..1] [215..1]
gi|73987517 - gi|73987517|ref|XP_855016.1| PREDICTED: similar to splicing factor 3a, subunit 2, 66kDa (predicted) ...
357.0 [0..1] [215..1]
gi|30931324 - gi|30931324|gb|AAH52697.1| Sf3a2 protein [Mus musculus]
356.0 [0..1] [215..1]
CG10754-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10754 (CG10754, FBgn0036314). It is a prote...
gi|220944472, gi... - gi|220954270|gb|ACL89678.1| CG10754-PA [synthetic construct], gi|220944472|gb|ACL84779.1| CG10754-PA...
355.0 [0..1] [214..1]
gi|118344168, gi... - gi|92081492|dbj|BAE93293.1| zinc finger protein [Ciona intestinalis], gi|118344168|ref|NP_001071907....
355.0 [0..1] [214..1]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYQNRAGVR FGGGGVAGYQ ETNAARRERL RKLALETIDL SKDPYLMKNH LGTFECRLCL  60
   61 TTHANENSYL THTQGKKHQT NLARRQALEN KKSQENAPQV LLGISQSHVQ VKKSVVKIGR 120
  121 PGYKVSKIRE AESGKFGLRF QIKY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.83
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.37529385176635 bayes_pls_golite062009
DNA binding 3.3049326844117 bayes_pls_golite062009
nucleic acid binding 3.24981360535232 bayes_pls_golite062009
snRNA binding 3.16782731106334 bayes_pls_golite062009
RNA binding 3.11293528368816 bayes_pls_golite062009
U1 snRNA binding 2.86343975521155 bayes_pls_golite062009
binding 2.84954567129719 bayes_pls_golite062009
transcription factor activity 2.44389510173662 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.57041104288348 bayes_pls_golite062009
mRNA binding 1.28525296322454 bayes_pls_golite062009
transcription activator activity 1.20323819132961 bayes_pls_golite062009
protein binding 0.975412203442928 bayes_pls_golite062009
sequence-specific DNA binding 0.732558534458316 bayes_pls_golite062009
transcription repressor activity 0.686318575498149 bayes_pls_golite062009
chromatin binding 0.626365497850853 bayes_pls_golite062009
transcription factor binding 0.515821187939278 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.200483461579207 bayes_pls_golite062009
transcription cofactor activity 0.113925660147477 bayes_pls_golite062009
structure-specific DNA binding 0.0855506955761403 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [145-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDIEVNAKPR YRIMSAYEQR VEAPDRKFQY LVVAAEPYES IAFKIDRAPG KFWSYWDAPT  60
   61 YTIQFFYNLT KIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle