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View Structure Prediction Details

Protein: clr1
Organism: Schizosaccharomyces pombe
Length: 1238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clr1.

Description E-value Query
Range
Subject
Range
gi|457146, gi|74... - pir||T28677 rhoptry protein - Plasmodium yoelii, gi|457146|gb|AAA21304.1| rhoptry protein [Plasmodi...
249.0 [0..108] [973..245]
gi|13195258 - gi|13195258|gb|AAK15626.1|AF323443_1 235 kDa rhoptry protein [Plasmodium yoelii yoelii]
247.0 [0..108] [973..720]
gi|83317448 - gi|83317448|ref|XP_731165.1| 235 kDa rhoptry protein [Plasmodium yoelii yoelii str. 17XNL]
gi|23491117 - gi|23491117|gb|EAA22730.1| 235 kDa rhoptry protein [Plasmodium yoelii yoelii]
246.0 [0..108] [973..719]
Strn-Mlck-PK - The gene Stretchin-Mlck is referred to in FlyBase by the symbol Dmel\Strn-Mlck (CG18255, FBgn0013988...
202.0 [0..100] [988..4264]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPDISSSE TLTELQQLRL LYFFCFYHAA PFNVKTLVHS LIPPGALSYL LSTYDILRPW  60
   61 LMALRVREGP VNDISTIVQL YEEIVKTGFF INPPPFESYS QTLVARITTL G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPKLQVQQEA QSEVYQRAST NTQQQVSNVS HGNFKPNSSV NTEPNTSILS NSKYAGIKPF  60
   61 DFQSSSQNPG LVCEQKTFYQ H

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [193-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFRPFSNLPS NKSSPVKHVS PNVKNNSKKT ASSVNSNHSS IPSSITKSNI SSLDVYGSEK  60
   61 LISSGSQQPG HGMVQTTSDK VNASASLYDR SPSKKDITSS R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.849 0.039 chromatin silencing at silent mating-type cassette a.60.9 lambda integrase-like, N-terminal domain

Predicted Domain #4
Region A:
Residues: [294-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTSSYNLGSM RNPSTLKNAA HANPFEGLRF QGSSAVLKEG LNSTVKKTFF DNLNSEKVC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [353-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVSPFLTPD NIASSILYST ASFSRSKPDR PRLNLSLELK LMQNELNKGQ LKKQFKGDLR  60
   61 NLADWNNLSL VSSKFPSLPI TNLRPDGSFL KHRRFNEEIA YNRQTLEKAI KQLDLSPDKV 120
  121 IQLREQNGVA VNGRVCYPTR NKHSEISAQS SSSLGVTKSL ASEVYSSSTV DTISKLNTDK 180
  181 DNYLIKSKKE PIQQKSVSSE TTLVKPSSTS SYIDTTNNVL KTNSSFKSSG LTSGPRNEKE 240
  241 LLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [596-701]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGIPTSHNNS ETQAQTADVS NIAASADGIY NSDQEKPPEK LDVTKRAFGR EIENSNEKEL  60
   61 LTSTFLSPSA ESQVCLAEIK TIRPGLVPKK QFSVDQNNVI SDNTDC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.08
Match: 1v65A
Description: Solution structure of the Kruppel-associated box (KRAB) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.35084112049258 bayes_pls_golite062009
DNA binding 2.22582111349682 bayes_pls_golite062009
binding 2.0499154380126 bayes_pls_golite062009
protein binding 0.477323490762673 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [702-933]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLPKPSNSKL SSISSDGDAS SNRMAVPDKS PFVHAAPNSK ALTKDSFSTH ISVSSLLHSD  60
   61 NEISPIDSTR KDYFTSKDSN LQTLKEDASS TKQAKDSGTN DFDKLISGND VSKNNSGEEQ 120
  121 SRSALKPLIS GKLSSCESIN LTKDISTVKR KEYFGIESTS SKQPFHDTGS IKIPAKRSFD 180
  181 TIDKDFRSSN IPFADKIKED GGDKNVISSI HITTELPKSM PVEVPTNAGA QS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [934-1238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQSNVVDSES LNLRENISTS VADVSLSQAG NEAVLSKKAC KPLVLIDPFE EKVLKAFNML  60
   61 SKGYAEYRCQ WEGCLANLHS LENFIKHVLL LHHPKSCSVV KCLWASCDMV LPSEEFEMHL 120
  121 RGHLNNIRLN CEVSNCKKCF SNYEDMFKHL QHSHLPFKFT PESFIKIRNG NVKEEARRTR 180
  181 NAYTQKSGEV ECFMETCTPI AKPAPANWYP VPPPGFNSSL LSRLTQSNQS KDKIIAALAK 240
  241 RNVYKSFAGL YDSKGKNDNT GYDFDSNYAR VGRHGSFILP VSKSVPTPSL LIEGSIVQRK 300
  301 NIKIE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.46
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle