YRC Public Data Repository - Protein Structure Prediction

Protein:	swc2
Organism:	Schizosaccharomyces pombe
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for swc2.

Description	E-value	Query Range	Subject Range
gi\|40253658, gi\|... - gi\|50941921\|ref\|XP_480488.1\| putative stress responsive gene 6 protein, Srg6 [Oryza sativa (japonica...	173.0	[0..11]	[315..15]
gi\|12054307, gi\|... - gi\|12054307\|emb\|CAC20595.1\| stress responsive gene 6, Srg6 [Hordeum vulgare subsp. vulgare], gi\|1205...	173.0	[0..10]	[315..16]
gi\|25408505, gi\|... - gi\|4415919\|gb\|AAD20150.1\| hypothetical protein [Arabidopsis thaliana], pir\|\|B84784 hypothetical prot...	172.0	[0..11]	[302..14]
gi\|109467177, gi... - gi\|34858037\|ref\|XP_227428.2\| PREDICTED: similar to Vacuolar protein sorting protein 72 homolog (Prot...	171.0	[0..6]	[304..2]
gi\|57098805 - gi\|57098805\|ref\|XP_533052.1\| PREDICTED: similar to YL-1 protein (Transcription factor-like 1) [Canis...	170.0	[0..6]	[304..2]
gi\|61368727, gi\|... - gi\|61368727\|gb\|AAX43227.1\| transcription factor-like 1 [synthetic construct], gi\|54695580\|gb\|AAV3816...	167.0	[0..6]	[304..2]
gi\|61358634, gi\|... - gi\|61358634\|gb\|AAX41598.1\| transcription factor-like 1 [synthetic construct], gi\|61358625\|gb\|AAX4159... VPS72 - vacuolar protein sorting 72 homolog (S. cerevisiae)	166.0	[0..6]	[304..2]
VPS72_PONPY - Vacuolar protein sorting-associated protein 72 homolog - Pongo pygmaeus (Orangutan) VPS72_PONAB - Vacuolar protein sorting-associated protein 72 homolog OS=Pongo abelii GN=VPS72 PE=2 SV=1	165.0	[0..6]	[304..2]
gi\|109016140 - gi\|109016140\|ref\|XP_001104866.1\| PREDICTED: transcription factor-like 1 [Macaca mulatta] gi\|163781015 - gi\|163781015\|gb\|ABY40791.1\| vacuolar protein sorting 72 homolog (predicted) [Papio anubis]	165.0	[0..6]	[304..2]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATESLVAG RTRRANAGNK MRELLEKEHL RMTQQNAEIE KEDEEYNIEE EEEAERDIEI  60
   61 SSESSDEEAE LKKLEEE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [78-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEEVEKILRD EERIKKRKIQ KNRAANLQRT LQPPKRPTPS AASEVPKKKY KKIKVDPSAR  60
   61 RTSSRMHTVL MAQSTETRLQ EAKPRRKYTV SASANRQKGT MTQQQRFEEA AKTEAQNLSS 120
  121 LRNYVHLEEQ RRLRLKRNAA KHRQLRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.09691
Match:	1dg3A
Description:	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [225-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PILKFISKTI STEDGREASN YYVAPLEHPL CHSAPPLQMP QHRAVECVIT GKPAIYLDPV  60
   61 TQLPISNVQA FQQVREVYNQ RYSWSAMLNL FH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.17
Match:	1x4sA
Description:	Solution structure of zinc finger HIT domain in protein FON
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.48298025894013	bayes_pls_golite062009
nucleic acid binding	2.27695396544623	bayes_pls_golite062009
DNA binding	2.13220564234684	bayes_pls_golite062009
binding	2.04387193075129	bayes_pls_golite062009
transcription activator activity	0.570282420961288	bayes_pls_golite062009
protein binding	0.520486355666439	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.512364998565023	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: