YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBPB10D8.02c
Organism:	Schizosaccharomyces pombe
Length:	554 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBPB10D8.02c.

Description	E-value	Query Range	Subject Range
gi\|107099172 - gi\|107099172\|ref\|ZP_01363090.1\| hypothetical protein PaerPA_01000182 [Pseudomonas aeruginosa PACS2] gi\|254243292, gi... - gi\|84324565\|ref\|ZP_00972622.1\| COG3119: Arylsulfatase A and related enzymes [Pseudomonas aeruginosa ... ARS_PSEAE - Arylsulfatase OS=Pseudomonas aeruginosa GN=atsA PE=1 SV=3 ARS_PSEAE - Arylsulfatase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=ats...	397.0	[0..9]	[540..2]
gi\|116053904, gi... - gi\|53726997\|ref\|ZP_00140606.2\| COG3119: Arylsulfatase A and related enzymes [Pseudomonas aeruginosa ...	397.0	[0..9]	[540..2]
gi\|49649187 - gi\|49649187\|emb\|CAG81525.1\| YALI0D26488p [Yarrowia lipolytica] gi\|49649187, gi\|... - gi\|50551689\|ref\|XP_503319.1\| YALI0D26488p [Yarrowia lipolytica], gi\|49649187\|emb\|CAG81525.1\| unnamed...	396.0	[0..5]	[553..1]
gi\|94413548 - gi\|94413548\|ref\|ZP_01293429.1\| hypothetical protein PaerP_01004723 [Pseudomonas aeruginosa PA7]	396.0	[0..9]	[533..2]
gi\|77380439, gi\|... - gi\|77456436\|ref\|YP_345941.1\| sulfatase [Pseudomonas fluorescens Pf0-1], gi\|77380439\|gb\|ABA71952.1\| a...	395.0	[0..9]	[542..2]
gi\|70733711, gi\|... - gi\|70733711\|ref\|YP_257351.1\| arylsulfatase [Pseudomonas fluorescens Pf-5], gi\|68348010\|gb\|AAY95616.1...	393.0	[0..9]	[542..2]
gi\|17942716, gi\|... - gi\|17942717\|pdb\|1HDH\|B Chain B, Arylsulfatase From Pseudomonas Aeruginosa, gi\|17942716\|pdb\|1HDH\|A Ch...	393.0	[0..9]	[540..2]
gi\|84318424, gi\|... - gi\|84318424\|ref\|ZP_00966848.1\| COG3119: Arylsulfatase A and related enzymes [Pseudomonas aeruginosa ...	392.0	[0..9]	[540..2]
gi\|66850995, gi\|... - gi\|70997211\|ref\|XP_753359.1\| arylsulfatase [Aspergillus fumigatus Af293], gi\|66850995\|gb\|EAL91321.1\|...	382.0	[0..9]	[538..43]

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Predicted Domain #1

Region A:
Residues: [1-554]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFNKQAESK KPNFLVIVAD DLGWSDVSPF GSEIHTPNIE RLAKEGVRLT NFHTASACSP  60
   61 TRSMLLSGTD NHIAGLGQMA ETVRRFSKVW GGKPGYEGYL NDRVAALPEI LQEAGYYTTM 120
  121 SGKWHLGLTP DRYPSKRGFK ESFALLPGGG NHFAYEPGTR ENPAVPFLPP LYTHNHDPVD 180
  181 HKSLKNFYSS NYFAEKLIDQ LKNREKSQSF FAYLPFTAPH WPLQSPKEYI NKYRGRYSEG 240
  241 PDVLRKNRLQ AQKDLGLIPE NVIPAPVDGM GTKSWDELTT EEKEFSARTM EVYAAMVELL 300
  301 DLNIGRVIDY LKTIGELDNT FVIFMSDNGA EGSVLEAIPV LSTKPPVKYF DNSLENLGNY 360
  361 NSFIWYGPRW AQAATAPSRL SKGFITEGGI RCPAIIRYPP LIKPDIISDE FVTVMDILPT 420
  421 ILELAEVPHP GHKFQGRDVV IPRGKPWIDH FVHGKPVHKD TDFSGWELFG QRAIRKGNYK 480
  481 AIYVPKEGIK TEWELYDLSQ DKGELENLAK VHPDILNELI EYWLVYEAET GVVTAPDDFV 540
  541 AENVGLFKPA KHNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	110.0
Match:	1hdhA
Description:	Arylsulfatase B (4-sulfatase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
sulfuric ester hydrolase activity	5.36665355899045	bayes_pls_golite062009
hydrolase activity	4.01787687283658	bayes_pls_golite062009
arylsulfatase activity	3.11969928063277	bayes_pls_golite062009
catalytic activity	2.31328968099128	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.25924473866143	bayes_pls_golite062009
steryl-sulfatase activity	1.90163490875396	bayes_pls_golite062009
binding	1.41800746903495	bayes_pls_golite062009
phosphatase activity	0.659886528405157	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.464622480235618	bayes_pls_golite062009
protein binding	0.208332656410563	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: