YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC1703.03c
Organism:	Schizosaccharomyces pombe
Length:	664 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1703.03c.

Description	E-value	Query Range	Subject Range
gi\|15680144 - gi\|15680144\|gb\|AAH14415.1\| HEATR3 protein [Homo sapiens]	401.0	[0..1]	[660..47]
gi\|114662452 - gi\|114662452\|ref\|XP_520630.2\| PREDICTED: HEAT repeat containing 3 [Pan troglodytes]	399.0	[0..1]	[660..81]
gi\|145019598, gi... - gi\|39971621\|ref\|XP_367201.1\| hypothetical protein MGG_07126 [Magnaporthe grisea 70-15], gb\|EAA56771....	393.0	[0..1]	[659..1]
gi\|73950410 - gi\|73950410\|ref\|XP_535308.2\| PREDICTED: similar to CG10286-PA [Canis familiaris]	389.0	[0..1]	[660..1]
HEAT3_MOUSE - HEAT repeat-containing protein 3 OS=Mus musculus GN=Heatr3 PE=1 SV=1	376.0	[0..1]	[660..1]
gi\|32415884, gi\|... - gi\|32415884\|ref\|XP_328420.1\| hypothetical protein [Neurospora crassa], gi\|28923902\|gb\|EAA33064.1\| pr... gi\|85107040 - gi\|85107040\|ref\|XP_962300.1\| hypothetical protein NCU07714 [Neurospora crassa OR74A]	372.0	[0..1]	[659..1]
gi\|117306260, gi... - gi\|76640397\|ref\|XP_586597.2\| PREDICTED: similar to CG10286-PA [Bos taurus], gi\|119910000\|ref\|XP_0012...	372.0	[0..1]	[660..1]

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Predicted Domain #1

Region A:
Residues: [1-394]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRANGKRRN HRKNRMNPIQ KKGFLEQEIP LNNSEAALPL LSRLDNPEIK ERSWACSAIS  60
   61 NIIASCTEGR LYLLKNGLVS KLIDRISDDS VEVVVEATGA LRNLAIEEGY SICMDMYRKN 120
  121 VLAPLQIWQT KIVQTLDEAT EGKNVLETYE DRSTFSCLCA IAENISSLLV NLGETTSQVI 180
  181 KVLNQKNTLV FLSRLLIPEA KIPQSVQEMA LQAFFTLTDD NDDGIITWIQ NSSDFALKTI 240
  241 NQIYLYFSYP SCLVRVYSIG IIYNIYQSGF VNKKMESVVK GISLFDSFIP EALPILSDLL 300
  301 PSEENYRNLV RQVYDKDTYF KTKKDDLTLS SELLVIPATL ELISSMTSLL QSLADGTDEL 360
  361 EEQEDSLMED EDLSYMDDMS NVVNEDENLI IDEI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.221849
Match:	1ejlI
Description:	Importin alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.68829442357484	bayes_pls_golite062009
protein binding	0.5289921716776	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [395-524]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSNTPQKGNF KLVEYMLDHV LPKVITYCVV AFEFSSEEIP SNLSNYFQEV GDRTIECLNN  60
   61 ISWSCNSVFV ESSEAFTRWK LSAGKILQWI FQTIFLRLGL GVWPFSSEGF TTACSLLWSV 120
  121 SKPFPAEIQV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [525-664]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSVDDISTLI LFSSTHGSLE AQSRLLGAFG SLGRCGNIQI NQLLGQTLMS CVIASDPNPL  60
   61 LAVEALNAIF DVYGDKSYPY DAPVFKGSGY LSQLSEALPR LKNMVKKIDR RREKHLRFRA 120
  121 EEALENLESF IDYKHAEYAS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: