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View Structure Prediction Details

Protein: ash2
Organism: Schizosaccharomyces pombe
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ash2.

Description E-value Query
Range
Subject
Range
gi|73979195 - gi|73979195|ref|XP_848878.1| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subun...
281.0 [0..11] [627..77]
ASH2L - ash2 (absent, small, or homeotic)-like (Drosophila)
gi|168277868 - gi|168277868|dbj|BAG10912.1| Set1/Ash2 histone methyltransferase complex subunit ASH2 [synthetic con...
281.0 [0..11] [627..77]
gi|76655880, gi|... - gi|76655880|ref|XP_870662.1| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subun...
280.0 [0..11] [627..78]
gi|114619679 - gi|114619679|ref|XP_001170172.1| PREDICTED: ash2 (absent, small, or homeotic)-like isoform 4 [Pan tr...
278.0 [0..11] [627..77]
ASH2L_MOUSE - Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Mus musculus GN=Ash2l PE=1 SV=1
278.0 [0..11] [627..72]
gi|109503505 - gi|109503505|ref|XP_214369.4| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subu...
278.0 [0..11] [627..72]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAHGSNDYG VSLKGNKTGS SPSKASSLNW NEPHTLNEQN TYCYCGKDRN LRFPDLQCSV  60
   61 CLNMFHLSCL SPPCTSMMGF STNYQFVCKH CTEDGFERFE RGVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 1wemA
Description: Solution structure of PHD domain in death inducer-obliterator 1(DIO-1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [105-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWKAITATAM ANLVVKRYVE TNPDVPVDSF NAEKMRNFQA NTYFFKKKED LIPFIEEHWQ  60
   61 LLCPDREKVQ TWQATLGSCL VANRDTYRAK DETMRNQNSE YALNNPNLFD FRSGYIFPFQ 120
  121 RVGATVPKKR LVETETPPPS SSKLKEDYKD SKREMKRSNT PWSNASIKKN EVPTVPIRY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.07
Match: 2hfhA
Description: THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [284-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPPWRDSDF ETVPKLPIFY PNSSSPNFFS LSEIPFNRRG FRYSPCEAAK DLPNV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [339-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYREIELPPF TSRINWHDIS TPVFIDHSAL CATVEKGFRM ARSNVFMTSG EWYFEIKIEK  60
   61 GGGDDGAHVR IGVSRREAPL DAPVGYDAYS YGLRDLGGQK VHMSRPRNFM DSFGTGDIIG 120
  121 LHISLPKPSF AQHTTLPSCH DRIPIRYKGQ LYFEQPDYVP SKMMDELMIP SKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.30103
Match: 2iwgB
Description: No description for 2iwgB was found.

Predicted Domain #5
Region A:
Residues: [512-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRYIDLPYIP GSFIKVYKNG SYMGTAFENL LDFNPPNSIN SNHYSFDDGS LGYYPSISMY  60
   61 GGGIARFQFG PQFSHRPLVL GSNVRPVSER YNEQIAEDVL CDILDEIDYA EDPNTSSVTI 120
  121 DVPQEPNAGI TIIPEIKDIT E

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 2fnjA
Description: No description for 2fnjA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle