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View Structure Prediction Details

Protein: ash2
Organism: Schizosaccharomyces pombe
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ash2.

Description E-value Query
Range
Subject
Range
gi|73979195 - gi|73979195|ref|XP_848878.1| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subun...
281.0 [0..11] [627..77]
ASH2L - ash2 (absent, small, or homeotic)-like (Drosophila)
gi|168277868 - gi|168277868|dbj|BAG10912.1| Set1/Ash2 histone methyltransferase complex subunit ASH2 [synthetic con...
281.0 [0..11] [627..77]
gi|76655880, gi|... - gi|76655880|ref|XP_870662.1| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subun...
280.0 [0..11] [627..78]
gi|114619679 - gi|114619679|ref|XP_001170172.1| PREDICTED: ash2 (absent, small, or homeotic)-like isoform 4 [Pan tr...
278.0 [0..11] [627..77]
ASH2L_MOUSE - Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Mus musculus GN=Ash2l PE=1 SV=1
278.0 [0..11] [627..72]
gi|109503505 - gi|109503505|ref|XP_214369.4| PREDICTED: similar to Set1/Ash2 histone methyltransferase complex subu...
278.0 [0..11] [627..72]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAHGSNDYG VSLKGNKTGS SPSKASSLNW NEPHTLNEQN TYCYCGKDRN LRFPDLQCSV  60
   61 CLNMFHLSCL SPPCTSMMGF STNYQFVCKH CTEDGFERFE RGVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 1wemA
Description: Solution structure of PHD domain in death inducer-obliterator 1(DIO-1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [105-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWKAITATAM ANLVVKRYVE TNPDVPVDSF NAEKMRNFQA NTYFFKKKED LIPFIEEHWQ  60
   61 LLCPDREKVQ TWQATLGSCL VANRDTYRAK DETMRNQNSE YALNNPNLFD FRSGYIFPFQ 120
  121 RVGATVPKKR LVETETPPPS SSKLKEDYKD SKREMKRSNT PWSNASIKKN EVPTVPIRY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.07
Match: 2hfhA
Description: THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [284-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPPWRDSDF ETVPKLPIFY PNSSSPNFFS LSEIPFNRRG FRYSPCEAAK DLPNV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [339-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYREIELPPF TSRINWHDIS TPVFIDHSAL CATVEKGFRM ARSNVFMTSG EWYFEIKIEK  60
   61 GGGDDGAHVR IGVSRREAPL DAPVGYDAYS YGLRDLGGQK VHMSRPRNFM DSFGTGDIIG 120
  121 LHISLPKPSF AQHTTLPSCH DRIPIRYKGQ LYFEQPDYVP SKMMDELMIP SKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.30103
Match: 2iwgB
Description: No description for 2iwgB was found.

Predicted Domain #5
Region A:
Residues: [512-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRYIDLPYIP GSFIKVYKNG SYMGTAFENL LDFNPPNSIN SNHYSFDDGS LGYYPSISMY  60
   61 GGGIARFQFG PQFSHRPLVL GSNVRPVSER YNEQIAEDVL CDILDEIDYA EDPNTSSVTI 120
  121 DVPQEPNAGI TIIPEIKDIT E

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 2fnjA
Description: No description for 2fnjA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle