YRC Public Data Repository - Protein Structure Prediction

Protein:	usp106
Organism:	Schizosaccharomyces pombe
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for usp106.

Description	E-value	Query Range	Subject Range
gi\|76652552 - gi\|76652552\|ref\|XP_615134.2\| PREDICTED: similar to Luc7 homolog (S. cerevisiae)-like isoform 1 [Bos ...	292.0	[0..3]	[234..5]
gi\|40744796, gi\|... - gi\|67522639\|ref\|XP_659380.1\| hypothetical protein AN1776.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	283.0	[0..1]	[235..1]
gi\|109473364 - gi\|109473364\|ref\|XP_001069518.1\| PREDICTED: similar to LUC7-like 2 [Rattus norvegicus]	283.0	[0..6]	[241..166]
gi\|42546284, gi\|... - gi\|46110621\|ref\|XP_382368.1\| hypothetical protein FG02192.1 [Gibberella zeae PH-1], gi\|42546284\|gb\|E...	278.0	[0..1]	[243..1]
gi\|38103284, gi\|... - gi\|39943494\|ref\|XP_361284.1\| hypothetical protein MGG_03758 [Magnaporthe grisea 70-15], gb\|EAA49999....	277.0	[0..1]	[233..1]
gi\|28921688, gi\|... - gi\|32410039\|ref\|XP_325500.1\| hypothetical protein [Neurospora crassa], gi\|28921688\|gb\|EAA30970.1\| hy... gi\|85096139 - gi\|85096139\|ref\|XP_960206.1\| hypothetical protein NCU05645 [Neurospora crassa OR74A]	272.0	[0..1]	[237..1]
gi\|113671672, gi... - gi\|113671672\|ref\|NP_001038784.1\| cisplatin resistance-associated overexpressed protein [Danio rerio]...	270.0	[0..5]	[247..4]
gi\|114191503, gi... - gi\|115400497\|ref\|XP_001215837.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	269.0	[0..1]	[235..1]
gi\|70991881, gi\|... - gi\|70991881\|ref\|XP_750789.1\| U1 snRNP splicing complex subunit (Luc7) [Aspergillus fumigatus Af293],... gi\|159124351 - gi\|159124351\|gb\|EDP49469.1\| U1 snRNP splicing complex subunit (Luc7), putative [Aspergillus fumigatu...	269.0	[0..1]	[235..1]
gi\|90306356, gi\|... - gi\|90306356\|gb\|EAS35987.1\| hypothetical protein CIMG_01341 [Coccidioides immitis RS], gi\|119193933\|r...	267.0	[0..1]	[253..1]

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Predicted Domain #1

Region A:
Residues: [1-76]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEQRKIIE QLMGSNLSNF TSRGLVHFTD RKVCRSFLCG ICPHDIFTNT KMDLGPCPKI  60
   61 HSDKLKSDYE RASYSH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.1
Match:	2d9mA
Description:	No description for 2d9mA was found.

Predicted Domain #2

Region A:
Residues: [77-177]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYGYEWDYLE DLERHVDDCN KRIDIAEARR EKTKEEEERI DELMRDIIHT DHSIEVIITE  60
   61 MEALAKRKLV NDAVKHFIEL NRLKTYRKEL YDEVISMNEI P

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.09691
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [178-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQASTTHQKL QVCDICSAYL SRLDNDRRLA DHFSGKMHLG YAMLRNIARD LRAQLEDREK  60
   61 SRDKKDGEKQ RDNLASFEDK ISTSFVA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.15
Match:	1uw2A
Description:	The structure of the zinc finger from the human spliceosomal protein U1C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
U1 snRNA binding	4.05926061907244	bayes_pls_golite062009
transcription regulator activity	3.37529385176635	bayes_pls_golite062009
DNA binding	3.3049326844117	bayes_pls_golite062009
nucleic acid binding	3.24981360535232	bayes_pls_golite062009
snRNA binding	3.16782731106334	bayes_pls_golite062009
RNA binding	3.11293528368816	bayes_pls_golite062009
binding	2.84954567129719	bayes_pls_golite062009
transcription factor activity	2.44389510173662	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.57041104288348	bayes_pls_golite062009
mRNA binding	1.28525296322454	bayes_pls_golite062009
transcription activator activity	1.20323819132961	bayes_pls_golite062009
protein binding	1.15986939995086	bayes_pls_golite062009
sequence-specific DNA binding	0.732558534458316	bayes_pls_golite062009
transcription repressor activity	0.686318575498149	bayes_pls_golite062009
chromatin binding	0.626365497850853	bayes_pls_golite062009
transcription factor binding	0.515821187939278	bayes_pls_golite062009
catalytic activity	0.263007611601737	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.200483461579207	bayes_pls_golite062009
transcription cofactor activity	0.113925660147477	bayes_pls_golite062009
structure-specific DNA binding	0.0855506955761403	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: