YRC Public Data Repository - Protein Structure Prediction

Protein:	sly1
Organism:	Schizosaccharomyces pombe
Length:	639 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sly1.

Description	E-value	Query Range	Subject Range
gi\|42544479, gi\|... - gi\|46137659\|ref\|XP_390521.1\| hypothetical protein FG10345.1 [Gibberella zeae PH-1], gi\|42544479\|gb\|E...	562.0	[0..6]	[634..2]
gi\|114652550 - gi\|114652550\|ref\|XP_509885.2\| PREDICTED: vesicle transport-related protein [Pan troglodytes]	557.0	[0..11]	[638..85]
gi\|73962930 - gi\|73962930\|ref\|XP_537403.2\| PREDICTED: similar to vesicle transport-related protein isoform a [Cani...	554.0	[0..5]	[638..2]
SCFD1_MOUSE - Sec1 family domain-containing protein 1 OS=Mus musculus GN=Scfd1 PE=1 SV=1	553.0	[0..7]	[638..7]
gi\|27465173, gi\|... - gi\|33504505\|ref\|NP_878281.1\| suppressor of ypt1 [Danio rerio], gi\|27817273\|emb\|CAD61086.1\| novel ves...	552.0	[0..8]	[638..1]
SCFD1_RAT - Sec1 family domain-containing protein 1 OS=Rattus norvegicus GN=Scfd1 PE=1 SV=1	552.0	[0..3]	[638..1]
gi\|70998945, gi\|... - gi\|70998945\|ref\|XP_754194.1\| Golgi transport protein Sly1 [Aspergillus fumigatus Af293], gi\|66851831... gi\|159127212 - gi\|159127212\|gb\|EDP52327.1\| Golgi transport protein Sly1, putative [Aspergillus fumigatus A1163]	549.0	[0..1]	[638..1]
gi\|34327968 - gi\|34327968\|dbj\|BAA74940.2\| KIAA0917 protein [Homo sapiens]	548.0	[0..11]	[638..20]

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Predicted Domain #1

Region A:
Residues: [1-639]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIASVKTPS SLREAQIQSL EKLLNLNQDV NELESSPQHA SNFPIWKVLI FDKAGSETIS  60
   61 SVLRISDLRK HGVTVHMNIT SFRQPIADVP AIYFVQPTQE NIELIIEDLS KGLYESAYVC 120
  121 FSSTISRALL EQFAELASKT NTSHMIHQVY DQYLNYVVLE SDFFSLQLPK IFHTFHNPSS 180
  181 DEALINSRVQ DIVNGLFSVI VTLGTIPIIR CPQGSAAEMV AQKLNQRLKD HLMNTKDAFV 240
  241 SVNPKPRPIL ILLDRTVDLI PMINHSWTYQ ALIHDTLNMQ LNRITVESVD DGKMTKRFYD 300
  301 LDGNDFFWES NASKPFPKVA ENIDEELTRY KNDASEITRK SGVSSLEEVN VDAFADSTYL 360
  361 KSAVSLLPEL TARKQILDMH MNIATALLKA IQERHLDDFF QLEDNITGLN RSAILACINN 420
  421 KEQGTPEDKL RFFIIWYLSV DSVPASDLQA YEEALVNNGC TLEALNFVKR VREITKMTML 480
  481 ASSTTRPATG QTGDNLFRGF SSLSTRFTDR FKEAGIGGLE NIISGVRNLI PFRKDGTITS 540
  541 IVQSLMDPGS SPASKQTESY LLLDPKSARA ITVNNDPRAM NKRQTFSEAI VCVLGGGNYL 600
  601 EYGNLADWAR EQNPKKRIIY GSTDILSPSE FMEEMASLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	142.0
Match:	1mqsA
Description:	Sly1P protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNARE binding	4.56428593085019	bayes_pls_golite062009
syntaxin binding	3.46044132736061	bayes_pls_golite062009
binding	2.5852206934785	bayes_pls_golite062009
protein binding	1.62257469066708	bayes_pls_golite062009
syntaxin-1 binding	0.269372794919901	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: