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View Structure Prediction Details

Protein: SPAC959.03c
Organism: Schizosaccharomyces pombe
Length: 520 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC959.03c.

Description E-value Query
Range
Subject
Range
gi|37523925, gi|... - gi|37523925|ref|NP_927302.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
386.0 [0..15] [437..742]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
379.0 [0..13] [515..1035]
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
379.0 [0..13] [467..1301]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
376.0 [0..15] [429..846]
gi|106891559, gi... - gi|148655047|ref|YP_001275252.1| WD-40 repeat-containing protein [Roseiflexus sp. RS-1], gi|14856715...
374.0 [0..11] [430..285]

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Predicted Domain #1
Region A:
Residues: [1-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAQKLNLED VNASTKKYSR GRKLNPKKIK DKKLRSNIQK IEERIENVES SLAKTEILHE  60
   61 DNPGLLEAEG LERTYKFRQD QLAPNVALET ATKSFSLDLD KFGGYSFDYT RDGRMILLGG 120
  121 RKGHISAFDW RTGKLLTELH LRETVRDVKW FHNHQYFAVA QKKYVYVYDN MGTEIHCLKR 180
  181 HIEVNALDFL PYHLLLTSIG NAGYLKYQDV STGQLVAEHR TGMGASHVLH QNPHNAVEHV 240
  241 GHANGQVTLW SPSSTTPLVK MLTHRGPVRD LAVNRDGRYM VTAGADSLLK VWDLRTYKEL 300
  301 HSYYTPTPAQ RLTLSDRGLL AVGWGPHATI WKDALRTKQN FPYMNHLLPS SSVVDLHYCP 360
  361 YEDILGIGHA KGFESIIVPG S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.154902
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 1.83286470399158 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
nucleic acid binding 1.20712373307552 bayes_pls_golite062009
structural molecule activity 1.20572493724069 bayes_pls_golite062009
protein binding 0.987581964031738 bayes_pls_golite062009
DNA binding 0.711274653406079 bayes_pls_golite062009
cytoskeletal protein binding 0.523052412917759 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009
ligase activity 0.00971558442368137 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [382-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEPNYDSYEN DPFASRKQRQ ETEVRQLLEK LRPEMISLNA DFIGNVDRAA PSLRKAEAEE  60
   61 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.30103
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [443-520]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPEEKWVPK AKARGKNSAL RRYLRKHARN VVDQRRLKVE KSLEIEKKMR AQRVRREQKL  60
   61 PEEREKWGYA LSRFVSKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle