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View Structure Prediction Details

Protein: SPAC24C9.11
Organism: Schizosaccharomyces pombe
Length: 775 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC24C9.11.

Description E-value Query
Range
Subject
Range
gi|71051531 - gi|71051531|gb|AAH31216.1| CWC22 protein [Homo sapiens]
514.0 [0..116] [775..9]
gi|38105561, gi|... - gi|39942982|ref|XP_361028.1| hypothetical protein MG03571.4 [Magnaporthe grisea 70-15], gb|EAA51976....
506.0 [0..7] [763..27]
CWC22_MOUSE - Pre-mRNA-splicing factor CWC22 homolog OS=Mus musculus GN=Cwc22 PE=1 SV=1
494.0 [0..117] [775..9]
gi|62645317, gi|... - gi|62645317|ref|XP_342454.2| PREDICTED: similar to CG12750-PA [Rattus norvegicus], gi|109470102|ref|...
492.0 [0..115] [775..5]
gi|90304122, gi|... - gi|90304122|gb|EAS33753.1| conserved hypothetical protein [Coccidioides immitis RS], gi|119189459|re...
491.0 [0..178] [775..50]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPIKKSRSL KLPKSILEEI GESDSSARRG KRNHNLPHRE KRKFARISRG KNGYENRKIT  60
   61 EEGDSKSSEL NDDYLDAHRK SSTKKKSSQN KQAKESKLLD PIAFQHKIAL EEDDREIAHL 120
  121 EKMLGIKSKD KSAHS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-222]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIDKEFGWLL EDLDQEIDDI GVPGTEDPSY GHSEDSEVSD DTGDHGSVDE LESEREGNSG  60
   61 EEEEEFHGFE SNSDEFHQPE TKPIRMD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [223-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLKPAVPSLP NANVGSKYVP PSLRKKLGGD KESEDALRLR RKLQGSLNKL SIANISSIIK  60
   61 EIEVLYMENS RHSVTSTITN LLLQTVMGRE SMLDQLAIVY AALATALYRI VGNDFGAHLL 120
  121 QTLVERFLQL YKSKEKEPLS SHKETSNLIV FFVELYNFQL VSCVLVYDLI RLFLRSLTEL 180
  181 NVEMLLKIVL NCGGQLRSDD PTSLQDIVTE MNLLLASADP STISVRTKFM VESITNLKEN 240
  241 KKTKVANASA QSKFEAVNQL KKFLGSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47395644967726 bayes_pls_golite062009
nucleic acid binding 1.72695422276859 bayes_pls_golite062009
structural molecule activity 1.66077840765881 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
transcription regulator activity 0.821718728559452 bayes_pls_golite062009
DNA binding 0.797151158461249 bayes_pls_golite062009
translation regulator activity 0.557943239197724 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.531544577163632 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
translation initiation factor activity 0.136474994339929 bayes_pls_golite062009
transcription factor activity 0.123371336741999 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [490-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNRSLNAREP LRVTLEDIEQ IETKGRWWLV GASWNNVPSG DNTLSTEALQ DKKKSEELTA  60
   61 HSKILQAAKK LRLNSTLRTS IFVALVGSED YIDAWERVLK LHLKRNQLPE IAYVILHCVG 120
  121 NEKLYNPFYG LVALKCCTLQ HNLKKSFQFS LWDFFNELQP DDDSEEREIS MRRIVNLAKL 180
  181 YASLVIEAAQ PLTILKHVDF MAINAQMQTF LLVFFTDIIL GVKDDLQLVK IFENCKAEKN 240
  241 LSSKVDWFLK TYVRKNPLVD NSKKALFKSN LAMASAILQS ISKEEI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.78
Match: 1n52A
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.36800795249393 bayes_pls_golite062009
nucleic acid binding 1.67566088591721 bayes_pls_golite062009
structural molecule activity 1.66038601649515 bayes_pls_golite062009
protein binding 0.914877292844892 bayes_pls_golite062009
transcription regulator activity 0.845665181662967 bayes_pls_golite062009
DNA binding 0.806448013051712 bayes_pls_golite062009
translation regulator activity 0.378889783888265 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.348192604482187 bayes_pls_golite062009
RNA binding 0.243875756041061 bayes_pls_golite062009
transcription factor activity 0.131703572961748 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle