YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC365.14c
Organism:	Schizosaccharomyces pombe
Length:	355 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC365.14c.

Description	E-value	Query Range	Subject Range
gi\|221325375 - gi\|221325375\|ref\|ZP_03606669.1\| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221321091 - gi\|221321091\|ref\|ZP_03602385.1\| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. JH64... gi\|221316179 - gi\|221316179\|ref\|ZP_03597984.1\| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. NCIB... GALE_BACSU - UDP-glucose 4-epimerase OS=Bacillus subtilis (strain 168) GN=galE PE=3 SV=1 GALE_BACSU - UDP-glucose 4-epimerase OS=Bacillus subtilis GN=galE PE=3 SV=1	295.0	[0..7]	[347..1]
gi\|37528640, gi\|... - gi\|37528640\|ref\|NP_931985.1\| UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) ...	292.0	[0..7]	[347..1]
gi\|75760496, gi\|... - gi\|75760496\|ref\|ZP_00740534.1\| UDP-glucose 4-epimerase / UDP-N-acetylglucosamine 4-epimerase [Bacil...	292.0	[0..7]	[351..1]
gi\|77960609, gi\|... - gi\|77960609\|ref\|ZP_00824473.1\| COG1087: UDP-glucose 4-epimerase [Yersinia mollaretii ATCC 43969], gi...	292.0	[0..7]	[346..1]
gi\|89201656, gi\|... - gi\|89201656\|ref\|ZP_01180393.1\| UDP-glucose 4-epimerase [Bacillus cereus subsp. cytotoxis NVH 391-98]...	290.0	[0..7]	[349..1]
UGE5_ARATH - UDP-glucose 4-epimerase 5 OS=Arabidopsis thaliana GN=UGE5 PE=1 SV=3	290.0	[0..4]	[347..1]
gi\|28809180 - gi\|28809180\|dbj\|BAC62222.1\| UDP-glucose 4-epimerase [Vibrio parahaemolyticus RIMD 2210633] gi\|28809180, gi\|... - gi\|28900734\|ref\|NP_800389.1\| UDP-glucose 4-epimerase [Vibrio parahaemolyticus RIMD 2210633], gi\|2880... gi\|153838095, gi... - gi\|153838095\|ref\|ZP_01990762.1\| UDP-glucose 4-epimerase [Vibrio parahaemolyticus AQ3810], gi\|1497484...	290.0	[0..7]	[346..1]
gi\|238723050, gi... - gi\|77973944\|ref\|ZP_00829488.1\| COG1087: UDP-glucose 4-epimerase [Yersinia frederiksenii ATCC 33641],...	289.0	[0..7]	[346..1]
gi\|42740565, gi\|... - gi\|42784633\|ref\|NP_981880.1\| UDP-glucose 4-epimerase [Bacillus cereus ATCC 10987], gi\|42740565\|gb\|AA...	289.0	[0..7]	[349..1]
gi\|74273840 - gi\|74273840\|gb\|ABA01568.1\| uridine diphosphate n-acetylgalactosamine 4-epimerase [Aeromonas hydrophi...	289.0	[0..7]	[348..1]

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Predicted Domain #1

Region A:
Residues: [1-355]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGVHEGTVL VTGGAGYIGS HTCVVLLEKG YDVVIVDNLC NSRVEAVHRI EKLTGKKVIF  60
   61 HQVDLLDEPA LDKVFANQNI SAVIHFAGLK AVGESVQVPL SYYKNNISGT INLIECMKKY 120
  121 NVRDFVFSSS ATVYGDPTRP GGTIPIPESC PREGTSPYGR TKLFIENIIE DETKVNKSLN 180
  181 AALLRYFNPG GAHPSGELGE DPLGIPNNLL PYIAQVAVGR LDHLNVFGDD YPTSDGTPIR 240
  241 DYIHVCDLAE AHVAALDYLR QHFVSCRPWN LGSGTGSTVF QVLNAFSKAV GRDLPYKVTP 300
  301 RRAGDVVNLT ANPTRANEEL KWKTSRSIYE ICVDTWRWQQ KYPYGFDLTH TKTYK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.39794
Match:	1z45A
Description:	Crystal structure of the gal10 fusion protein galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae complexed with NAD, UDP-glucose, and galactose
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-glucose 4-epimerase activity	2.13934644118967	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.03956654822048	bayes_pls_golite062009
nucleic acid binding	0.868888700854563	bayes_pls_golite062009
binding	0.835119783772935	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.82673050487418	bayes_pls_golite062009
DNA binding	0.790382977752475	bayes_pls_golite062009
transcription regulator activity	0.613310508772122	bayes_pls_golite062009
transcription factor activity	0.11102650759187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: