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View Structure Prediction Details

Protein: mbx2
Organism: Schizosaccharomyces pombe
Length: 372 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mbx2.

Description E-value Query
Range
Subject
Range
gi|34452083 - gi|34452083|gb|AAQ72498.1| MADS-box protein 12 [Petunia x hybrida]
236.0 [0..1] [234..1]
gi|62122355 - gi|62122355|dbj|BAD93172.1| MADS-box transcription factor GbMADS8 [Ginkgo biloba]
233.0 [0..1] [233..1]
gi|31747208 - gi|31747208|gb|AAP57412.1| MADS-box protein 1 [Lycopersicon esculentum]
228.0 [0..1] [234..1]
gi|34979582 - gi|34979582|gb|AAQ83835.1| MADS box protein [Asparagus officinalis]
227.0 [0..1] [232..1]
gi|89258366 - gi|89258366|gb|ABD65406.1| MADS-box protein [Diospyros kaki]
227.0 [0..1] [234..1]
gi|63014399 - gi|63014399|gb|AAY25580.1| AGL6 [Amborella trichopoda]
226.0 [0..1] [232..1]
gi|1206005, gi|7... - pir||T09571 MADS box protein MADS2 - Monterey pine, gi|1206005|gb|AAD09207.1| putative MADS-box fami...
226.0 [0..1] [233..1]
gi|1702951, gi|7... - pir||T10486 MADS box protein - Canadian red pine, gi|1702951|emb|CAA70822.1| MADS-box family transcr...
226.0 [0..1] [233..1]
gi|63094573 - gi|63094573|gb|AAY30858.1| MADS-box transcription factor [Prunus dulcis]
225.0 [0..1] [234..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRKKISIAP ITDDRSRSVT FVKRKQGLYK KAYELAVLAD CEVAVTVIDR KGRLHVFCSS  60
   61 DYQRTLQQLN TLSIYELKNR SHFSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.221849
Match: 1tqeP
Description: Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.20423226810641 bayes_pls_golite062009
DNA binding 3.19357863925229 bayes_pls_golite062009
binding 3.13725722282473 bayes_pls_golite062009
transcription regulator activity 3.13318816174147 bayes_pls_golite062009
transcription factor activity 2.59884999361198 bayes_pls_golite062009
sequence-specific DNA binding 2.01575603719104 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.0615361674883 bayes_pls_golite062009
protein binding 1.0452482001033 bayes_pls_golite062009
transcription activator activity 0.69462470268703 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [86-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVEESSTVS PETTTGSFTP LNNKHLKSQD QPLSDSQLDT GDSPATSETT VQDYNPQVQS  60
   61 YCRPEPLSSN HVRSCPPFPP TQHHHPHTRP PHHPPHPHFH NNNYPPPYCF QSPV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [200-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPGATVPLQH HSPYPSDNGF PGHRRQTHFA PYYYPQRATS PSLKQVPTYL GTHVLQQDQS  60
   61 TYDQKVLMPP ASYLSSPNQY TLKNVSPGNP ACPPFLYEHP NPQLTPEMFD VKQGSPIPPT 120
  121 AYSGSSCETS QHTIANTPFL AYDRSPSLTN QEAESSFQDV ASISPHSLSD VKY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle