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View Structure Prediction Details

Protein: tfg1
Organism: Schizosaccharomyces pombe
Length: 490 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tfg1.

Description E-value Query
Range
Subject
Range
orf19.12054, orf... - TFG1 CGDID:CAL0002912 Assembly 19, Contig19-10212 (36896, 38722) CDS, translated using codon table 1...
gi|68466350, gi|... - gi|68466350|ref|XP_722657.1| hypothetical protein CaO19.4585 [Candida albicans SC5314], gi|68466055|...
175.0 [0..15] [393..5]
gi|26346919 - gi|26346919|dbj|BAC37108.1| unnamed protein product [Mus musculus]
174.0 [0..29] [253..2]
gi|50555874, gi|... - gi|50555874|ref|XP_505345.1| YALI0F12815p [Yarrowia lipolytica], gi|49651215|emb|CAG78152.1| unnamed...
gi|49651215 - gi|49651215|emb|CAG78152.1| YALI0F12815p [Yarrowia lipolytica]
169.0 [0..34] [383..54]
gi|32406206, gi|... - gi|40882261|emb|CAF06086.1| related to transcription initiation factor TFIIF large subunit [Neurospo...
gi|85078253 - gi|85078253|ref|XP_956136.1| hypothetical protein NCU04363 [Neurospora crassa OR74A]
163.0 [0..25] [358..80]
gi|11514679, gi|... - gi|11514683|pdb|1F3U|H Chain H, Crystal Structure Of The Rap3074 INTERACTION DOMAINS OF Human Tfiif,...
152.0 [0..29] [221..1]
gi|50427445, gi|... - gi|50427445|ref|XP_462335.1| hypothetical protein DEHA0G19459g [Debaryomyces hansenii CBS767], gi|49...
152.0 [0..38] [385..35]
gi|42550747, gi|... - gi|46116844|ref|XP_384440.1| hypothetical protein FG04264.1 [Gibberella zeae PH-1], gi|42550747|gb|E...
152.0 [0..20] [415..62]
gi|55962454 - gi|55962454|emb|CAI11478.1| novel protein similar to X. laevis transcription initiation factor IIF, ...
152.0 [0..46] [417..18]

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Predicted Domain #1
Region A:
Residues: [1-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSQETKVFE NVKQENPDEK KPKVEEPDSQ NNASTQSQQK FLDFQLSWCP ESERKTTKYH  60
   61 LLKFHSNKAI DPSKSFVPPI KMQRRDPNAP SSSNGEQNAE QGSSSNVNIA SIAPYGGAQN 120
  121 MKQNAFKRKT RQVVKVDPQA RRLQEEELSP WIMEDFEGKN TWVSTMEGGQ SSAYVLFMFS 180
  181 ENGFKVIPTD RFYRFNQRNN FQTLSIDEAE AKMNKKTPIP R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 1f3uB
Description: TFIIF alpha subunit, Rap74
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 10.2797850053222 bayes_pls_golite062009
transcription initiation factor activity 6.22439849848084 bayes_pls_golite062009
RNA polymerase II transcription factor activity 4.06672086326535 bayes_pls_golite062009
transcription regulator activity 3.89911747857156 bayes_pls_golite062009
binding 2.6963272883422 bayes_pls_golite062009
transcription coactivator activity 1.30173573105398 bayes_pls_golite062009
protein binding 1.06175937412568 bayes_pls_golite062009
transcription activator activity 0.800371882273381 bayes_pls_golite062009
transcription factor binding 0.677361513203971 bayes_pls_golite062009
transcription cofactor activity 0.43974291826617 bayes_pls_golite062009
catalytic activity 0.304516551414824 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [222-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WFMKKESEEN LAEAGSASPM YKLKTVPNAR PVTGPRASGS DDELDYDEEF ADDEEAPIME  60
   61 GNEEDNKKLK DKIKKEMLTA NLFGEADQDV DLEEENDRQM SREGKKLQRY LKLLEKNLAY 120
  121 ESDEEDEDPY ASSHDASSEE EVLQEEEELQ KREEKLKSRF SANASKTNTP RPLERTPSSV 180
  181 SPVKASSQLQ S

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [413-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNTSIQIRPQ EQLINKPGYI ILRLSSEKLS RFANDFPRMV PSMGSTETSV GDQVEVVGDT  60
   61 TNVPIDGMLK FYIYQKIY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle