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View Structure Prediction Details

Protein: nep2
Organism: Schizosaccharomyces pombe
Length: 415 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nep2.

Description E-value Query
Range
Subject
Range
gi|30017488, gi|... - gi|34896768|ref|NP_909728.1| putative transposon protein [Oryza sativa (japonica cultivar-group)], g...
218.0 [0..10] [307..1355]

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Predicted Domain #1
Region A:
Residues: [1-262]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSNSIFTKE IDSEAVKKSS NLRPPSTGSS NSNGSDTASP KKKKKGFFRS LFGSSSSGSK  60
   61 SCGSPFTRIW LEYFEVSLRK NDVDHFRPGY WILDTNIDFF YEIMLRQVLL KRPKEESQQI 120
  121 YLLRPAMVFF LAQAPNPLEI ESALPPAMFD ASFIFLPIND TNECGIESGS HWSLLVVSVE 180
  181 KGLGWYYDSM SNGNTNDCNL AIKNLGILLK KEFRVRHMKT PQQINDCDCG LHVCENTRIL 240
  241 MYRLLQKPYV PKVDMNLDHS VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.09691
Match: 1tgzA
Description: Structure of human Senp2 in complex with SUMO-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine-type peptidase activity 6.54685807643041 bayes_pls_golite062009
small conjugating protein-specific protease activity 6.39247995905454 bayes_pls_golite062009
ubiquitin-specific protease activity 5.52987342617304 bayes_pls_golite062009
ubiquitin thiolesterase activity 3.91170685383331 bayes_pls_golite062009
peptidase activity 3.28868056127375 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.01472402774099 bayes_pls_golite062009
SUMO-specific protease activity 2.65263825059319 bayes_pls_golite062009
hydrolase activity 2.29464693834116 bayes_pls_golite062009
endopeptidase activity 2.26699762664334 bayes_pls_golite062009
thiolester hydrolase activity 2.16768752586311 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.3276268995308 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 1.01104209091599 bayes_pls_golite062009
NEDD8-specific protease activity 0.687958315289315 bayes_pls_golite062009
nucleic acid binding 0.439226369799415 bayes_pls_golite062009
calcium-dependent cysteine-type endopeptidase activity 0.196538841514154 bayes_pls_golite062009
DNA binding 0.168761518285256 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.144331158319621 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [263-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVRLRKALM EVITSLLAAY GSKVPKPSET HTDPEKDKKI FSKICKTEEL LELPTLSAVT  60
   61 SDSAQPHSLP ASMPSSQPQS RSESLPLTHP NSEPNPKLDS QPNSSPVRRP SLIKVKTAST 120
  121 SVLPTSILQR PPSIVPRPET AAIQHTQQSI EIH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.34
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
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