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View Structure Prediction Details

Protein: SPBC21B10.13c
Organism: Schizosaccharomyces pombe
Length: 201 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC21B10.13c.

Description E-value Query
Range
Subject
Range
gi|9621907 - gi|9621907|gb|AAF89581.1|AF165886_1 paired-box transcription factor [Branchiostoma floridae]
121.0 [0..14] [197..170]
gi|8920423, gi|1... - gi|8920423|emb|CAB96423.1| OCL3 protein [Zea mays], gi|162462506|ref|NP_001105125.1| outer cell laye...
118.0 [0..7] [200..94]
gi|15823130 - gi|15823130|dbj|BAB68716.1| homeobox protein [Mus musculus musculus]
tr|Q920T7|Q920T7... - tr|Q920T7|Q920T7_MOUSE Homeobox protein (Fragment) OS=Mus musculus GN=Hoxa2 PE=2 SV=1, Homeobox prot...
116.0 [0..27] [199..7]
gi|15823132 - gi|15823132|dbj|BAB68717.1| homeobox protein [Mus spicilegus]
gi|15823120, gi|... - gi|15823128|dbj|BAB68715.1| homeobox protein [Mus musculus], gi|15823126|dbj|BAB68714.1| homeobox pr...
gi|15823118 - gi|15823118|dbj|BAB68710.1| homeobox protein [Mus musculus musculus]
116.0 [0..27] [199..7]
gi|33339721, gi|... - gi|45383171|ref|NP_989830.1| transcription factor Crx [Gallus gallus], gi|33339721|gb|AAQ14340.1|AF2...
116.0 [0..14] [198..19]
gi|114583567 - gi|114583567|ref|XP_001165353.1| PREDICTED: paired box gene 3 isoform 5 [Pan troglodytes]
114.0 [0..7] [193..198]
gi|38636822, gi|... - gi|50940895|ref|XP_479975.1| putative OCL5 protein [Oryza sativa (japonica cultivar-group)], gi|4639...
113.0 [0..1] [197..134]
gi|109101200 - gi|109101200|ref|XP_001107509.1| PREDICTED: paired box gene 3 (Waardenburg syndrome 1) isoform 5 [Ma...
113.0 [0..7] [193..193]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSDSPSKS GNTGKDLISN NEAKNHEDEE THQKKRRRRT TDAEATLLEQ YFLKTPKPSL  60
   61 IERQELSKKL KSSMTPRELQ IWFQNKRQSL RRSNCLSRNR LEG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1pufA
Description: Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [104-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGENSLLRRK STLTLCETST GQAELFFQSW PLHSQSVVGE MIHHEQDDYN KENKQQKVVD  60
   61 TTKDISRGSN GNEDSAAHQE LEECARSLVE LQQQCNDH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle