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View Structure Prediction Details

Protein: sfc1
Organism: Schizosaccharomyces pombe
Length: 456 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sfc1.

Description E-value Query
Range
Subject
Range
gi|7493050 - gi|7493050|pir||T11662 probable transcription factor 44K chain - fission yeast (Schizosaccharomyces...
506.0 [0..83] [439..1]
gi|110737985 - gi|110737985|dbj|BAF00928.1| hypothetical protein [Arabidopsis thaliana]
423.0 [0..6] [401..13]
gi|46123035, gi|... - gi|46123035|ref|XP_386071.1| hypothetical protein FG05895.1 [Gibberella zeae PH-1], gi|42550843|gb|E...
410.0 [0..2] [387..38]
gi|145014741, gi... - gi|39944016|ref|XP_361545.1| hypothetical protein MGG_04019 [Magnaporthe grisea 70-15], gb|EAA50260....
409.0 [0..2] [381..27]
gi|67902020, gi|... - gi|67902020|ref|XP_681266.1| hypothetical protein AN7997.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
395.0 [0..2] [379..10]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLKISDNE YALIEHPGFA NNKDAFFQTL GGVQSIQKAC QTSFQNPKQA LLELNLRPKD  60
   61 KYHHPVQARV QSRNDLLVTI KKMDNSVQNV SRIRQVFLFR D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADFQYSTQN SPFVQKLDST LRVLDYNAIN KFSIDLTPVQ RKHVDMPPPP VFSQTSLPMS  60
   61 YNFLQNPLVG RVRLPNGKTT IVNLKGQCRV WIITTNMGVE SVPTCRHSKL GEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [215-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKTIQEVIEA LKPLFEKRPV WTRRALLNHL DPSYTHYLKF ALPYLSYLWT SGPFRDTYTR  60
   61 FGYDPRKDSN AAAYQALFFK LKLNGKH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.06
Match: 1bbyA
Description: DNA-BINDING DOMAIN FROM HUMAN RAP30, NMR, MINIMIZED AVERAGE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.23858959608048 bayes_pls_golite062009
DNA binding 4.54024488199476 bayes_pls_golite062009
nucleic acid binding 4.30331577005505 bayes_pls_golite062009
transcription factor activity 3.82269332595313 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 3.35557958497305 bayes_pls_golite062009
binding 3.17811844148923 bayes_pls_golite062009
transcription activator activity 2.13702350917359 bayes_pls_golite062009
sequence-specific DNA binding 2.12567455635303 bayes_pls_golite062009
transcription repressor activity 1.9708626903609 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.50332889556988 bayes_pls_golite062009
transcription factor binding 0.752335897765285 bayes_pls_golite062009
protein binding 0.626618806841206 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [302-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGTKTHVFDG KTLFPTNRVY QVCDIVDPTI APLLKDTQLR SECHRDTGWY RSGRYYKVRD  60
   61 LMREKLFALI EGEMPSEVAV NMILNAEEVE ESDRYSNFDE QDNTDLNDTV RGLNTSATDD 120
  121 RINDLMRNLM KRSQEHEGFE DLEEIDDDYD DIFGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle