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View Structure Prediction Details

Protein: SPAC6G9.14
Organism: Schizosaccharomyces pombe
Length: 681 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC6G9.14.

Description E-value Query
Range
Subject
Range
PUM1_ARATH - Pumilio homolog 1 OS=Arabidopsis thaliana GN=APUM1 PE=1 SV=1
483.0 [0..3] [673..212]
gi|73950040 - gi|73950040|ref|XP_865141.1| PREDICTED: similar to pumilio 1 isoform 1 isoform 6 [Canis familiaris]
481.0 [0..15] [658..366]
gi|114576347 - gi|114576347|ref|XP_001140088.1| PREDICTED: pumilio homolog 2 isoform 4 [Pan troglodytes]
480.0 [0..34] [658..381]
gi|20513851 - gi|20513851|gb|AAM22812.1|AF427791_3 BPM [Hordeum vulgare]
479.0 [0..37] [669..239]
gi|24159015, gi|... - gi|24159016|pdb|1M8Y|B Chain B, Crystal Structure Of The Pumilio-Homology Domain From Human Pumilio1...
478.0 [0..324] [658..2]
PUM1_XENLA - Pumilio homolog 1 OS=Xenopus laevis GN=pum1 PE=1 SV=1
478.0 [0..70] [658..545]
PUM1_CHICK - Pumilio homolog 1 OS=Gallus gallus GN=PUM1 PE=2 SV=1
477.0 [0..15] [658..486]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEQSSKSHP SFMSTEYSLP VFSSQYSDIE NKDVLKSNSW DPYAANAPIA LSEIPSSSKS  60
   61 GKTNGSKAAV ESGLASGAFG NRTGNMNRNT SMSGYTFGSS NFVPYNLLSN TPSFTT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHSSSTTFVP PATMGGGLNN LSSPSSSLYL PGSASYQRSN SKNSSASILQ MNTTLDDIPI  60
   61 LLRRPGLSSY TPGPSTSRRS ISSSSNLGGN PGLIANNPSA SKNFAFTSGS SSTNNSTTSS 120
  121 SSMANGLQSI SKHSAAFP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [255-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLSNATSFFG ENLTPSLAAS TASTGSTDSS GSNIANTLIA PTPTISPPSA NTVGNPSPAD  60
   61 TPGFNVPSLI SDDPSVSSSL S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [336-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVASLSLQN SNILSFCKDQ HGCRYLQRLL EKKNQSHIDA VFAETHPYLA VLMVDAFGNY  60
   61 LCQKLFEHAS EAQRSTFIQI IAPKLVPISF NMHGTRALQK IIDLVSSPDQ ISCIVNALRP 120
  121 NVVLLTKDLN GNHVIQKCLN KFSQEDCQFI FDAICEDPLD VSTHRHGCCV VQRCFDHASP 180
  181 AQIEQLVEHI VPHALTLVQD AFGNYVLQYV LELNNPNHTE AIISYFLYKV RALSTQKFSS 240
  241 NVMEKCIFFA PAAIKEKLIS ELMDEKHLPK LLRDSFANYV IQTALDNASV KQRAELVERI 300
  301 KPLIPSIKNT PCGRRILSKL ERRHPSSKEK PIVYSNSERV NTSSSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.0
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.11573661150436 bayes_pls_golite062009
binding 1.83406697369076 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
nucleic acid binding 0.967597910409065 bayes_pls_golite062009
mRNA binding 0.73831124805124 bayes_pls_golite062009
hydrolase activity 0.0579816100130538 bayes_pls_golite062009
transcription regulator activity 0.022274123463527 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle