YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC1F12.05
Organism:	Schizosaccharomyces pombe
Length:	377 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1F12.05.

Description	E-value	Query Range	Subject Range
gi\|85085596 - gi\|85085596\|ref\|XP_957526.1\| hypothetical protein NCU03887 [Neurospora crassa OR74A] gi\|32405186, gi\|... - gi\|32405186\|ref\|XP_323206.1\| hypothetical protein [Neurospora crassa], gi\|28918619\|gb\|EAA28290.1\| co...	295.0	[0..4]	[372..2]
gi\|46128141, gi\|... - gi\|46128141\|ref\|XP_388624.1\| hypothetical protein FG08448.1 [Gibberella zeae PH-1], gi\|42548061\|gb\|E...	287.0	[0..3]	[375..2]
gi\|49083900, gi\|... - gi\|67515549\|ref\|XP_657660.1\| hypothetical protein AN0056.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	278.0	[0..3]	[369..80]
gi\|38102563, gi\|... - gi\|39973617\|ref\|XP_368199.1\| hypothetical protein MGG_01045 [Magnaporthe grisea 70-15], gb\|EAA49387....	271.0	[0..3]	[375..2]
gi\|114195277, gi... - gi\|115387375\|ref\|XP_001211193.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	270.0	[0..3]	[363..81]
gi\|159126874 - gi\|159126874\|gb\|EDP51990.1\| conserved hypothetical protein [Aspergillus fumigatus A1163] gi\|66851035, gi\|... - gi\|70997299\|ref\|XP_753399.1\| arrestin (or S-antigen), N-terminal domain protein [Aspergillus fumigat...	267.0	[0..3]	[372..82]
gi\|83772836 - gi\|83772836\|dbj\|BAE62964.1\| unnamed protein product [Aspergillus oryzae] gi\|220692932, gi... - gi\|238499889\|ref\|XP_002381179.1\| arrestin (or S-antigen), N-terminal domain protein [Aspergillus fla... gi\|169779265 - gi\|169779265\|ref\|XP_001824097.1\| hypothetical protein [Aspergillus oryzae RIB40]	266.0	[0..5]	[369..88]
CE16301 - status:Partially_confirmed UniProt:O17982 protein_id:CAB05787.1	263.0	[0..18]	[377..4]

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Predicted Domain #1

Region A:
Residues: [1-100]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLVRRFQH ASTEEQPFEL NIQMESPPLV MYGNPDVSSG ALASGLAKLT VFPADLKCES  60
   61 IVMEFVRIIS TKRPLRDSCP DCKAQVEAFE KWEFSKEPTV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [101-377]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTHGTHTWPF TFIIPGHFPQ TTNSPFINVT YILKTRVKIP SQPDFVFEYP LNLKRSIVTN  60
   61 ADKIAQRLFP PTSLIALLEL PPVIHPLSCV PVEFQLTGVK PENSKVGWRL TKISWRIEEQ 120
  121 IKAQINGCST HTGTKKPYIF KETRLLGNNE HKSGWKEDGD RIIFEIPIST SLLSKPICDV 180
  181 SFDGQFSLYI AHQLILETIV VEVMNSHPIN SNARILRMKV NLPLTERGGL GVSWDEECPP 240
  241 MFNSVGPSPP AYEQVARSSP TDIPLPPPSC PTNVQRD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.69897
Match:	1jsyA
Description:	Arrestin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
clathrin binding	2.75916108281518	bayes_pls_golite062009
binding	2.5075656948209	bayes_pls_golite062009
protein binding	1.71025015568774	bayes_pls_golite062009
substrate-specific transporter activity	0.929966017205863	bayes_pls_golite062009
potassium channel activity	0.871728492941793	bayes_pls_golite062009
voltage-gated cation channel activity	0.848303301157398	bayes_pls_golite062009
voltage-gated ion channel activity	0.829939555243379	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.829140804686535	bayes_pls_golite062009
voltage-gated channel activity	0.820413268771765	bayes_pls_golite062009
channel activity	0.796075411518814	bayes_pls_golite062009
passive transmembrane transporter activity	0.796075411518814	bayes_pls_golite062009
substrate-specific channel activity	0.790863065462458	bayes_pls_golite062009
voltage-gated potassium channel activity	0.787347074261486	bayes_pls_golite062009
cation channel activity	0.770955130885998	bayes_pls_golite062009
ion transmembrane transporter activity	0.760234877475175	bayes_pls_golite062009
ion channel activity	0.743051345681968	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.735623329949285	bayes_pls_golite062009
cation transmembrane transporter activity	0.698762820554681	bayes_pls_golite062009
gated channel activity	0.62499749903999	bayes_pls_golite062009
inward rectifier potassium channel activity	0.43450134854604	bayes_pls_golite062009
ligand-gated channel activity	0.302082279531376	bayes_pls_golite062009
ligand-gated ion channel activity	0.302082279531376	bayes_pls_golite062009
cytoskeletal protein binding	0.24498703916422	bayes_pls_golite062009
actin binding	0.15943777627145	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: