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View Structure Prediction Details

Protein: usp109
Organism: Schizosaccharomyces pombe
Length: 352 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for usp109.

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
239.0 [0..1] [350..110]
gi|76689263 - gi|76689263|ref|XP_880772.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
237.0 [0..1] [350..110]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
236.0 [0..1] [350..110]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
236.0 [0..1] [350..110]

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Predicted Domain #1
Region A:
Residues: [1-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEDYIRAIF ENVRKVNYYE DGESGAILKT CCIEFESQDA ARNALERQST QRLISGNPIS  60
   61 LDVVPEWQKP SYYMLFISNI DPEVSENDIK YLFQRYNFIS ARVLRCVDGT STSIAFIWLA 120
  121 NESDIQNAQV EMQGAFCLKR SILVHSVKSD KNTYLSSPGF YGTPQPLNQF TDPNNTAVYV 180
  181 HQLPENITTQ ELRSYFLHFG EILYTQVNNN SGRIVFAQRY FAEQAINEMN NFPLHGVRIQ 240
  241 LSWARPPSMA LLPSKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2ghpA
Description: No description for 2ghpA was found.

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
U1 snRNA binding 4.22094068431436 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [257-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STYWPALAAP VYPSMKDVPN NPFTPFSPIN PYYAKSWNHT ASAPLLPPGL KNGSDYPYLS  60
   61 VPPDILNDSY LAMCEAVNSR LDAESTMLLP VHYSQA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle