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View Structure Prediction Details

Protein: SPAC4G8.03c
Organism: Schizosaccharomyces pombe
Length: 780 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4G8.03c.

Description E-value Query
Range
Subject
Range
gi|125572616, gi... - gi|34908236|ref|NP_915465.1| putative pumilio/Mpt5 family RNA-binding protein [Oryza sativa (japonic...
474.0 [0..5] [780..242]
gi|24159015, gi|... - gi|24159016|pdb|1M8Y|B Chain B, Crystal Structure Of The Pumilio-Homology Domain From Human Pumilio1...
473.0 [0..443] [777..2]
gi|73950046 - gi|73950046|ref|XP_865198.1| PREDICTED: similar to pumilio 1 isoform 1 isoform 8 [Canis familiaris]
471.0 [0..23] [777..247]
gi|114576343 - gi|114576343|ref|XP_001140348.1| PREDICTED: pumilio homolog 2 isoform 6 [Pan troglodytes]
470.0 [0..17] [777..292]

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Predicted Domain #1
Region A:
Residues: [1-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNRDAYNEL NLNKKSQETN RKPSPLSSYT SISRELDYAN QSPFSSNSFS PTELKARTSA  60
   61 TFDVRSASTS PINASDFHKY SHDPFQRLFK AKGNASFSKT KSFPSSVTYS PSEETFPLTS 120
  121 GMNKSVHEYP FTLSESAISS SHKSSIPERR NFDSSVSVSN PLLHWNNVDT LLRDGSLENV 180
  181 NNSRQDQFLP YKTFSSTISN SDFLHRESSF SSLIDEESKL ASLRNLNIND RPPLPVLKNS 240
  241 ERNLLHRQLL SNHPFFSQNN VSLSTNSKNY STDFTKIQS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [280-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSSLLQNRQQ NHRIETDQLS HFPDHLDPSR IPSPYQPSSL QPLESRKLHS KVDVHSKKLN  60
   61 ALSQLNPILR SENVLQNDNH HSSLSMDNDP TNVSTKNRNN QTVGEHPYVD DNKKKKKGPA 120
  121 KPKEKATLGK TVNSFFGSHS TSNYSKVPLS AKLTGEKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [438-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDLSNLLKNK GKKKSQDNQI PHLVGFLGHL STICKDQYGC RYLQKLLDEN PKVNASLFFP  60
   61 EIRQSVVQLM IDPFGNYMCQ KLFVYASREQ KLSMLNGIGE GIVDICSNLY GTRSMQNIID 120
  121 KLTSNEQISL LLKIIIPSLT TLACDNNGTH VLQKCIAKFP PEKLEPLFLS MEENLITLAT 180
  181 NRHGCCILQR CLDRTNGDIQ ERLVNSIIKS CLLLVQNAYG NYLVQHVLEL NIQPYTERII 240
  241 EKFFGNICKL SLQKFSSNAI EQCIRTASPS TREQMLQEFL SFPNIEQLLD DCYANYVMQR 300
  301 FLNVADESQK FLILRSISHV IPKIQNTRHG RHILAKLTSS TSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.0
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.11573661150436 bayes_pls_golite062009
binding 2.04462323043166 bayes_pls_golite062009
nucleic acid binding 1.25530318108311 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
mRNA binding 0.73831124805124 bayes_pls_golite062009
transcription regulator activity 0.464230801825493 bayes_pls_golite062009
DNA binding 0.356030945125909 bayes_pls_golite062009
hydrolase activity 0.0579816100130538 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle