YRC Public Data Repository - Protein Structure Prediction

Protein:	vps45
Organism:	Schizosaccharomyces pombe
Length:	558 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps45.

Description	E-value	Query Range	Subject Range
gi\|7321218, gi\|1... - gi\|7321218\|emb\|CAA73264.2\| sec1-like protein [Loligo pealei], gi\|13096246\|pdb\|1FVH\|A Chain A, Crysta...	545.0	[0..1]	[554..1]
gi\|39953684, gi\|... - gi\|39953684\|ref\|XP_364007.1\| hypothetical protein MG08852.4 [Magnaporthe grisea 70-15], gb\|EAA46509....	545.0	[0..1]	[552..1]
gi\|85109616 - gi\|85109616\|ref\|XP_963004.1\| vacuolar protein sorting-associated protein 45 [Neurospora crassa OR74A... gi\|32411133, gi\|... - gi\|32411133\|ref\|XP_326047.1\| hypothetical protein [Neurospora crassa], gi\|28924651\|gb\|EAA33768.1\| va...	543.0	[0..1]	[552..1]
gi\|114051133, gi... - gi\|84708888\|gb\|AAI11246.1\| Syntaxin binding protein 2 [Bos taurus], gi\|114051133\|ref\|NP_001039673.1\|...	543.0	[0..3]	[558..6]
STXBP2 - syntaxin binding protein 2 gi\|208967548 - gi\|208967548\|dbj\|BAG73788.1\| syntaxin binding protein 2 [synthetic construct]	543.0	[0..3]	[558..6]
gi\|197102274 - gi\|197102274\|ref\|NP_001124900.1\| syntaxin binding protein 2 [Pongo abelii] gi\|55726287 - gi\|55726287\|emb\|CAH89915.1\| hypothetical protein [Pongo abelii]	542.0	[0..3]	[558..6]
STXB2_MOUSE - Syntaxin-binding protein 2 OS=Mus musculus GN=Stxbp2 PE=1 SV=1	540.0	[0..1]	[558..4]
STXB2_CANLF - Syntaxin-binding protein 2 OS=Canis lupus familiaris GN=STXBP2 PE=2 SV=1	538.0	[0..3]	[558..6]

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Predicted Domain #1

Region A:
Residues: [1-558]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVSASQSY FKRIFQEVSD LKILLLEEDT TKIVSSCITQ SNLLEQQIYL TVLLGNKREK  60
   61 LRHLKCVAFL RPTPTTLRLL CEELRDPKYA EYHLYFTNVI PKSFLERLAE SDDFEAVKSI 120
  121 QEFFLDYLVV NNDLASFNIP HIIEDSPDNW QDGAFHRTHQ GIISLLLSLK KKPVIRYDNN 180
  181 SLLCLKLAEE VSYTIQHESQ LFNFRKPDTA PILLLLDRKN DPITPLLTQW TYQAMVHELF 240
  241 GIDNGRVSFS NSTSDNEKST EIVLNPTLDP FYKETRFDNF GDLGVKIKDY VSHLQTKSTK 300
  301 KASEIESIAD MKQFLEAYPE YRRLSGNVSK HVSLVSEISQ VVQRENLLEV GEVEQSLVCN 360
  361 EPQSTDFNDI QRLLFSNISE NTKLRLAALY SLRFERIDPA KVSALQQMLI AGGVNPLKVS 420
  421 VIPTLLHVAG YSFRQGDVFP PSNLFSRARS GLKGLRGVEN VYIQHNPFLK SILLDLIQGR 480
  481 LKETTHPFLN SETRAQTSNE KPQDIIVVIV GGATYEEAHF VSEFNATQPG VRIILAGTTI 540
  541 LNSTAYIDDI MYMSTRIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.0
Match:	1epuA
Description:	Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNARE binding	4.56428593085019	bayes_pls_golite062009
syntaxin binding	3.46044132736061	bayes_pls_golite062009
binding	2.7837022903231	bayes_pls_golite062009
protein binding	2.77285532000616	bayes_pls_golite062009
syntaxin-1 binding	0.269372794919901	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: