YRC Public Data Repository - Protein Structure Prediction

Protein:	vps33
Organism:	Schizosaccharomyces pombe
Length:	592 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps33.

Description	E-value	Query Range	Subject Range
gi\|7321218, gi\|1... - gi\|7321218\|emb\|CAA73264.2\| sec1-like protein [Loligo pealei], gi\|13096246\|pdb\|1FVH\|A Chain A, Crysta...	536.0	[0..3]	[583..1]
gi\|118405042, gi... - gi\|118405042\|ref\|NP_001072521.1\| syntaxin binding protein 1 [Xenopus (Silurana) tropicalis], gi\|1152...	525.0	[0..3]	[583..4]
gi\|29378335 - gi\|29378335\|gb\|AAO83849.1\|AF484092_1 neural-specific syntaxin-binding protein 1 [Lymnaea stagnalis]	524.0	[0..3]	[591..1]
ENSMMUG000000164... - null, null ENSCJAT00000038932 - null tr\|F6R0H3\|F6R0H3... - Isoform of P61763, Syntaxin-binding protein 1 OS=Bos taurus GN=STXBP1 PE=4 SV=1 gi\|119608087, gi... - gi\|57208971\|emb\|CAI41180.1\| syntaxin binding protein 1 [Homo sapiens], gi\|4507297\|ref\|NP_003156.1\| s... gi\|165972307, gi... - gi\|21594764\|gb\|AAH31728.1\| Stxbp1 protein [Mus musculus], gi\|165972307\|ref\|NP_001107041.1\| syntaxin ... gi\|149038988, gi... - gi\|755493\|gb\|AAA96350.1\| rbSec1B, gi\|149038988\|gb\|EDL93208.1\| syntaxin binding protein 1, isoform CR...	524.0	[0..4]	[583..5]
gi\|17225417 - gi\|17225417\|gb\|AAL37391.1\|AF326545_1 syntaxin binding protein 1 [Mus musculus]	522.0	[0..4]	[592..5]
STXB1_CHICK - Syntaxin-binding protein 1 OS=Gallus gallus GN=STXBP1 PE=2 SV=1	522.0	[0..4]	[592..5]
STXB1_PONAB - Syntaxin-binding protein 1 OS=Pongo abelii GN=STXBP1 PE=2 SV=1 STXB1_BOVIN - Syntaxin-binding protein 1 OS=Bos taurus GN=STXBP1 PE=1 SV=1 STXB1_MOUSE - Syntaxin-binding protein 1 OS=Mus musculus GN=Stxbp1 PE=1 SV=2 gi\|123997501, gi... - gi\|157929000\|gb\|ABW03785.1\| syntaxin binding protein 1 [synthetic construct], gi\|123997501\|gb\|ABM863... STXB1_RAT - Syntaxin-binding protein 1 OS=Rattus norvegicus GN=Stxbp1 PE=1 SV=1 gi\|999002 - gi\|999002\|gb\|AAB34080.1\| p67=67 kda neuronal-specific protein [rats, brain, Peptide, 594 aa] STXB1_PONPY - Syntaxin-binding protein 1 - Pongo pygmaeus (Orangutan) STXBP1 - syntaxin binding protein 1 ENSMMUT000000230... - null, null	522.0	[0..4]	[592..5]
gi\|435430, gi\|73... - gi\|738775\|prf\|\|2001428B syntaxin-binding synaptic protein, gi\|435430\|gb\|AAB41112.1\| Munc18-1 [Bos ta...	521.0	[0..4]	[592..5]
gi\|51261450, gi\|... - gi\|51261450\|gb\|AAH80023.1\| LOC100101272 protein [Xenopus laevis], gi\|153792420\|ref\|NP_001093335.1\| h...	521.0	[0..3]	[592..4]

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Predicted Domain #1

Region A:
Residues: [1-592]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDVKEKAT FKLLDLIDSV TGKKSLLLER DLSGILGQIV TTNTLQEHGI PQVYWFNENI  60
   61 PNDIEKKTIY LCRPTYENAK LVATHVRQFQ RDMLRIESTV IVLPTSNILF ETVLQEEGVF 120
  121 GELLVTEWPL HAVPLDKDLL SLELGPEKLE ESLLQRSTDA LIDFERTHGR FPRVSGRGPY 180
  181 AAKMLELLEK TYQEEATINF GKVEGEISAL YDSVLLVDRS LDRITPFLTQ LTYFGFLDEI 240
  241 LGIQQMNVKL PSSLVNRNEA SNTGPMKKFS LSSSSSQITK EIRDINFNCI GPYLSKIARK 300
  301 LSSDFEGRRQ AKTVNQIRDF VSKLGSLQSE HTSLNIHTGL AETLVQHTKN NYFQKLLQLQ 360
  361 HLLVSHADSF TQFNLLDEII YAEAPVEEVF RVLCLASITT NGLRRKDIDH YRREITQTYG 420
  421 YYHLLTFQAL IDAGLLRLRQ STNISLQKSL SYSTWLNTYP LVKDEVDEQN PEDIAYTYSG 480
  481 YGPLSVHIAY DILKGRDNEE KILKLQNMPG TYVDKWTLDQ EKVMPKNLKT NVPGKRRVLV 540
  541 FFIGGCTYTE LAAFRLLQEK EDLYEFTFMT TGMVTGSSLI RAFIPNIESL NE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	153.0
Match:	1epuA
Description:	Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNARE binding	3.42828022195984	bayes_pls_golite062009
binding	2.7837022903231	bayes_pls_golite062009
syntaxin binding	2.11416428645287	bayes_pls_golite062009
protein binding	1.7224010512877	bayes_pls_golite062009
syntaxin-1 binding	0.269372794919901	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: