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View Structure Prediction Details

Protein: SPCC1223.09
Organism: Schizosaccharomyces pombe
Length: 296 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1223.09.

Description E-value Query
Range
Subject
Range
URIC_ASPFL - Uricase OS=Aspergillus flavus GN=uaZ PE=1 SV=3
gi|114795210 - gi|114795210|gb|ABI79319.1| urate oxidase [Aspergillus niger]
gi|83774942 - gi|83774942|dbj|BAE65065.1| unnamed protein product [Aspergillus oryzae]
gi|169783472 - gi|169783472|ref|XP_001826198.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|238493269, gi... - gi|238493269|ref|XP_002377871.1| urate oxydase UaZ [Aspergillus flavus NRRL3357], gi|220696365|gb|EE...
450.0 [0..7] [295..4]
gi|28924766, gi|... - gi|32416162|ref|XP_328559.1| hypothetical protein [Neurospora crassa], gi|28924766|gb|EAA33878.1| ur...
gi|85109841 - gi|85109841|ref|XP_963114.1| uricase [Neurospora crassa OR74A]
447.0 [0..6] [295..3]
URIC_EMENI - Uricase OS=Emericella nidulans GN=uaZ PE=3 SV=1
URIC_EMENI - Uricase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=uaZ P...
444.0 [0..6] [296..3]
gi|116191661, gi... - gi|88181461|gb|EAQ88929.1| hypothetical protein CHGG_05548 [Chaetomium globosum CBS 148.51], gi|1161...
443.0 [0..7] [295..4]
gi|11230981 - gi|11230981|dbj|BAB18098.1| uricase [Tolypocladium inflatum]
439.0 [0..6] [295..3]
gi|62953146 - gi|62953146|emb|CAG28680.1| uricase [Gibberella fujikuroi]
436.0 [0..6] [295..3]
gi|11230971 - gi|11230971|dbj|BAB18095.1| uricase [Geisha distinctissima yeast-like symbiont]
434.0 [0..6] [295..3]
gi|42549485, gi|... - gi|46116568|ref|XP_384302.1| hypothetical protein FG04126.1 [Gibberella zeae PH-1], gi|42549485|gb|E...
434.0 [0..6] [295..3]

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Predicted Domain #1
Region A:
Residues: [1-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETTYVKQC AYGKTLVRFM KKDICPKTKT HTVYEMDVQS LLTGELEESY TKADNSIVVP  60
   61 TDTQKNTIYV FAKNNDVSVP EVFAAKLAKH FVDKYKHIHG AALDITITPW TRMEVQGKPH 120
  121 SHSFIRNPGE TRKTHVVFSE GKGFDVVSSL KDVLVLKSTG SGFTNFHKCE FTTLPEVTDR 180
  181 IFSTSIDCNY TFKHFDTFEE LAGFDFNSIY EKVKEITLET FALDDSESVQ ATMYKMADTI 240
  241 INTYPAINEV YYALPNKHYF EINLAPFNID NLGSNCSLYQ PQAYPSGYIT CTVARK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.0
Match: 1r4sA
Description: URATE OXIDASE FROM ASPERGILLUS FLAVUS COMPLEXED WITH ITS INHIBITOR 9-METHYL URIC ACID
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
urate oxidase activity 4.98056582061231 bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor 4.31732265940848 bayes_pls_golite062009
GTP cyclohydrolase I activity 3.71208106424087 bayes_pls_golite062009
catalytic activity 2.20788162511962 bayes_pls_golite062009
GTP cyclohydrolase activity 1.89570925022701 bayes_pls_golite062009
cyclohydrolase activity 1.8212867268343 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.73101699306211 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.974891318710762 bayes_pls_golite062009
binding 0.876314139116894 bayes_pls_golite062009
dihydroneopterin aldolase activity 0.803156673865251 bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity 0.756899305060565 bayes_pls_golite062009
hydrolase activity 0.734877553662152 bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors 0.448906913739211 bayes_pls_golite062009
oxidoreductase activity 0.0310611456658956 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle