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View Structure Prediction Details

Protein: uap2
Organism: Schizosaccharomyces pombe
Length: 367 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for uap2.

Description E-value Query
Range
Subject
Range
gi|76633759 - gi|76633759|ref|XP_882155.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
190.0 [0..1] [351..72]
gi|73992493 - gi|73992493|ref|XP_534430.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 1 [Canis fam...
188.0 [0..1] [351..72]

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Predicted Domain #1
Region A:
Residues: [1-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQPFWDER IHRWRCLGSE GNELIYIDEE QTWKDYDPNS LKMNKAGSTG AEVSDVTAEA  60
   61 TEGKESSNGE DRHTKRLYES TSAEGYPSGS RNKKSKSENS EASPAPVINK AVYIQGLPLD 120
  121 VTVDEIEEVF KKCGVIAKNI DNGTPRIKIY RTEDGTPKGD ALIVFFRSES VELAEQLFDD 180
  181 TEFRYGSGQK MRVQKANIDY KKEKTVNKDV GGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 2adbA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [214-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKKKALRLRQ QQMQQISSWD DVDEEVDDKR KKRFNKIVVL KHIFTLEELD KTPELLIDLK  60
   61 DDITEEAEKC GRVTNVVLYD KEPDGVVTVR FSNNEEAEAC VRLMQGRYFD GRVVEASIYD 120
  121 GKVRFQKSGK HTLDDEEDEE KRLEKFADWL ENSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2ditA
Description: No description for 2ditA was found.

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle