YRC Public Data Repository - Protein Structure Prediction

Protein:	ste4
Organism:	Schizosaccharomyces pombe
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ste4.

Description	E-value	Query Range	Subject Range
gi\|39976873, gi\|... - gi\|39976873\|ref\|XP_369824.1\| hypothetical protein MG06339.4 [Magnaporthe grisea 70-15], gb\|EAA56368....	185.0	[0..3]	[260..57]
gi\|46122213, gi\|... - gi\|46122213\|ref\|XP_385660.1\| hypothetical protein FG05484.1 [Gibberella zeae PH-1], gi\|42550974\|gb\|E...	184.0	[0..3]	[260..55]
gi\|85081729 - gi\|85081729\|ref\|XP_956774.1\| hypothetical protein NCU00455 [Neurospora crassa OR74A] gi\|28917851, gi\|... - gi\|32403856\|ref\|XP_322541.1\| hypothetical protein [Neurospora crassa], gi\|28917851\|gb\|EAA27538.1\| co...	182.0	[0..5]	[218..63]
gi\|45199225, gi\|... - gi\|45199225\|ref\|NP_986254.1\| AFR706Cp [Ashbya gossypii ATCC 10895], gi\|44985365\|gb\|AAS54078.1\| AFR70... gi\|44985365 - gi\|44985365\|gb\|AAS54078.1\| AFR706Cp [Ashbya gossypii ATCC 10895]	180.0	[0..30]	[262..85]
STE50 - Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adap... STE50_YEAST - Protein STE50 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE50 PE=1 SV=1	176.0	[0..5]	[262..29]
gi\|25137304 - gi\|25137304\|emb\|CAD44493.2\| MAPKK kinase [Emericella nidulans] gi\|40744686, gi\|... - gi\|67523627\|ref\|XP_659873.1\| hypothetical protein AN2269.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	171.0	[0..3]	[260..55]
gi\|11119233 - gi\|11119233\|gb\|AAG30572.1\|AF312696_1 mekk [Pneumocystis carinii]	170.0	[0..8]	[261..7]
gi\|71002732, gi\|... - gi\|71002732\|ref\|XP_756047.1\| MAPKKK cascade protein kinase regulator Ste50 [Aspergillus fumigatus Af... gi\|159130101 - gi\|159130101\|gb\|EDP55215.1\| protein kinase regulator Ste50 [Aspergillus fumigatus A1163] gi\|28394449 - gi\|28394449\|gb\|AAM08676.1\| Ste50p [Aspergillus fumigatus]	161.0	[0..8]	[208..64]
gi\|116208032, gi... - gi\|88183906\|gb\|EAQ91374.1\| hypothetical protein CHGG_03309 [Chaetomium globosum CBS 148.51], gi\|1162...	160.0	[0..3]	[260..18]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDSDDFYWN WNNEAVCNWI EQLGFPHKEA FEDYHILGKD IDLLSSNDLR DMGIESVGHR  60
   61 IDILSAIQSM KKQQKDKLQQ ENKDQELKNI EESYKKLEEK TEHLSDDNVS LEKRVEYLET 120
  121 ENTKLVKTLN SLNSEFLQLL RKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.30103
Match:	2eaoA
Description:	No description for 2eaoA was found.

Predicted Domain #2

Region A:
Residues: [144-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AINVKEGRQL TTENSSDTSS MTHPVQPSPS VLGSFDLEVN DSLTNAEKNR KLNVNLTYNE  60
   61 VLCSMLQRYR IDPNTWMSYD LLINYDDKEH AIPMDVKPLQ LFRNLQKRGK SPSFVLSRRS 120
  121 C

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.79
Match:	1wxaA
Description:	Solution Structure of Ras-binding Domain in Mouse AF-6 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.0688320293797	bayes_pls_golite062009
protein binding	1.72968950672856	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: