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View Structure Prediction Details

Protein: ste11
Organism: Schizosaccharomyces pombe
Length: 468 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ste11.

Description E-value Query
Range
Subject
Range
gi|101091, gi|5103 - gi|5103|emb|CAA77507.1| ste11 [Schizosaccharomyces pombe], pir||A41518 transcription factor ste11 - ...
182.0 [0..1] [468..1]
gi|87280846 - gi|87280846|gb|ABD36562.1| polycystic kidney disease 1-like 3 variant 1b [Mus musculus]
153.0 [0..117] [463..267]
gi|3511287, gi|7... - pir||T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain - Mastigamoeba invertens (frag...
151.0 [0..141] [393..1429]
gi|54657094 - gi|54657094|gb|EAL35927.1| DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain [Cryptosporidiu...
gi|67597591 - gi|67597591|ref|XP_666157.1| DNA-directed RNA polymerase II largest chain [Cryptosporidium hominis T...
148.0 [0..68] [391..1554]
gi|12642614 - gi|12642614|gb|AAK00311.1|AF315821_1 DNA-dependent RNA polymerase II largest subunit RPB1 [Monosiga ...
133.0 [0..116] [405..1421]
gi|83767526, gi|... - gi|9955855|dbj|BAB12227.1| RNA polymerase II largest subunit [Aspergillus oryzae], gi|83767526|dbj|B...
gi|169770395 - gi|169770395|ref|XP_001819667.1| hypothetical protein [Aspergillus oryzae RIB40]
123.0 [0..124] [358..1506]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLTAEQK DQKSSVKRPL NSFMLYRRDR QAEIPTSNHQ SISRIIGQLW RNESAQVKKY  60
   61 YSDLSALERQ KHMLENPEYK YTPKKRSTVR RRHKKVSPSS GSFVASDYVV LQQIAQSSKT 120
  121 LKQTEPEKPV NEEETLAALL APALSYPKSG KSNLIETSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2gzkA
Description: No description for 2gzkA was found.

Predicted functions:

Term Confidence Notes
DNA binding 5.15324651287773 bayes_pls_golite062009
nucleic acid binding 5.01228762819617 bayes_pls_golite062009
transcription regulator activity 4.9607192917135 bayes_pls_golite062009
sequence-specific DNA binding 4.06355503548774 bayes_pls_golite062009
transcription factor activity 3.82658263870186 bayes_pls_golite062009
binding 3.6211482127468 bayes_pls_golite062009
transcription activator activity 2.95665802871704 bayes_pls_golite062009
protein binding 2.18211240370246 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.84606709725198 bayes_pls_golite062009
transcription repressor activity 1.53825678633232 bayes_pls_golite062009
transcription factor binding 1.10315330167937 bayes_pls_golite062009
chromatin binding 0.996049314969019 bayes_pls_golite062009
DNA bending activity 0.87985209274756 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.426897554228699 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [160-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSCLSSSPMI RSHTIPSLSF TDQVSTTIST LDKSEQAPSS LGIYYRSPSS GSPIGRTKSV  60
   61 CLANKARIVP KRSMSSDGCV DKSYQMSKTP SLEAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [255-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPQNSSNCSA RRVPKFDSKG TVSEQSNSDS PELSADKVLS HCSPIDARPS TPSCPNASIS  60
   61 PKTPNTGDHY GFDGAEYLGT PLSVGSTTAY LYGQETELLS TPYCHTSYPA MSRLNSSSGY 120
  121 TCVSSSSVTN SGHTENNTWR SDEQSKGFVD INSFSQSLFS NGNYEFAAHS QELDDLFSQI 180
  181 TDFTSTDPIA SSLKDANSLG PSLLEPWLPN SNLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle