YRC Public Data Repository - Protein Structure Prediction

Protein:	sce3
Organism:	Schizosaccharomyces pombe
Length:	388 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sce3.

Description	E-value	Query Range	Subject Range
gi\|76633747 - gi\|76633747\|ref\|XP_881817.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	204.0	[0..21]	[386..35]
gi\|82934588, gi\|... - gi\|82934588\|ref\|XP_484034.3\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...	199.0	[0..20]	[386..34]
gi\|1082703, gi\|6... - gi\|693937\|emb\|CAA88401.1\| polyadenylate binding protein II [Homo sapiens], pir\|\|S52491 polyadenylate...	199.0	[0..21]	[386..10]
gi\|73974132 - gi\|73974132\|ref\|XP_856753.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	199.0	[0..21]	[386..35]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPKKSTKMS LNAFLGDESF GSTNWADDID DLPALPQDRT TSTYRATPSS ADAGYNAPSS  60
   61 TFESVRSPPE SRREGGMGSG YQRDAIPIPS EPPFTAHVGN LSFDLTENDL GDFFGEGVTS 120
  121 IRLVIDPLTE RSRGFGYVEF ETADTLSAAL ALSGEDLMGR PVRITVAEPR RSFAREERST 180
  181 GDWVRRGP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1pgzA
Description:	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.85623936961615	bayes_pls_golite062009
RNA binding	2.05010436328789	bayes_pls_golite062009
nucleic acid binding	1.47284776517711	bayes_pls_golite062009
protein binding	1.32954276279597	bayes_pls_golite062009
mRNA binding	0.487879052146416	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [189-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPAEPAESP FGKRRTNSGR FRDPARDPSD RVREEPREWV RRGPLPPRES SERPRLNLKP  60
   61 RSSSNVNTEA TPSATTTTSS KPKRDPFGGA KPVDNTSVLQ RVEEKLAKRT QSFRREDNAN 120
  121 RERSTSRKPS ADKAEKTDKT DAIAEKVSDI RLGDGEKKSS ETDSEVAATK TPATEDAPAT 180
  181 NAGEAEEEEG WTKIGKGRKH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.13
Match:	2j63A
Description:	No description for 2j63A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: