YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC2F7.17
Organism:	Schizosaccharomyces pombe
Length:	396 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC2F7.17.

Description	E-value	Query Range	Subject Range
RF1_PASMU - Peptide chain release factor 1 OS=Pasteurella multocida (strain Pm70) GN=prfA PE=3 SV=1 RF1_PASMU - Peptide chain release factor 1 OS=Pasteurella multocida GN=prfA PE=3 SV=1	466.0	[0..33]	[394..1]
gi\|68058123, gi\|... - gi\|68249924\|ref\|YP_249036.1\| peptide chain release factor 1 [Haemophilus influenzae 86-028NP], gi\|68...	464.0	[0..33]	[394..2]
RF1_HAEIN - Peptide chain release factor 1 OS=Haemophilus influenzae GN=prfA PE=3 SV=2 RF1_HAEIN - Peptide chain release factor 1 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)...	463.0	[0..33]	[394..1]
RF1_HAEIN - (P43917) Peptide chain release factor 1 (RF-1) gi\|148716243, gi... - gi\|148826083\|ref\|YP_001290836.1\| peptide chain release factor 1 [Haemophilus influenzae PittEE], gi\|... gi\|144982593, gi... - gi\|145642039\|ref\|ZP_01797610.1\| peptide chain release factor 1 [Haemophilus influenzae R3021], gi\|14... gi\|145637543, gi... - gi\|145637543\|ref\|ZP_01793200.1\| peptide chain release factor 1 [Haemophilus influenzae PittHH], gi\|1... gi\|145631803, gi... - gi\|145642039\|ref\|ZP_01797610.1\| peptide chain release factor 1 [Haemophilus influenzae R3021], gi\|14... gi\|16273461, gi\|... - gi\|16273461\|ref\|NP_439710.1\| peptide chain release factor 1 [Haemophilus influenzae Rd KW20], gi\|157... gi\|229809952, gi... - gi\|229847123\|ref\|ZP_04467228.1\| peptide chain release factor 1 [Haemophilus influenzae 7P49H1], gi\|2... gi\|229844233, gi... - gi\|229844233\|ref\|ZP_04464374.1\| peptide chain release factor 1 [Haemophilus influenzae 6P18H1], gi\|2...	463.0	[0..33]	[394..2]
RF1_HAES1 - Peptide chain release factor 1 OS=Haemophilus somnus (strain 129Pt) GN=prfA PE=3 SV=1	461.0	[0..33]	[394..1]
gi\|53732835 - gi\|53732835\|ref\|ZP_00155134.2\| COG0216: Protein chain release factor A [Haemophilus influenzae R2846...	461.0	[0..33]	[394..2]
RF1_PSEU2 - Peptide chain release factor 1 OS=Pseudomonas syringae pv. syringae (strain B728a) GN=prfA PE=3 SV=1	460.0	[0..33]	[393..1]
RF1_PSE14 - Peptide chain release factor 1 OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) GN...	460.0	[0..33]	[393..1]
RF1_PSEE4 - Peptide chain release factor 1 OS=Pseudomonas entomophila (strain L48) GN=prfA PE=3 SV=1 gi\|95109087 - gi\|95109087\|emb\|CAK13784.1\| peptide chain release factor 1 [Pseudomonas entomophila L48]	459.0	[0..33]	[393..1]
RF1_VIBCM - Peptide chain release factor 1 OS=Vibrio cholerae serotype O1 (strain M66-2) GN=prfA PE=3 SV=1 gi\|116189311, gi... - gi\|75830361\|ref\|ZP_00759641.1\| COG0216: Protein chain release factor A [Vibrio cholerae MO10], gi\|25... gi\|229355248, gi... - gi\|229507743\|ref\|ZP_04397248.1\| peptide chain release factor 1 [Vibrio cholerae BX 330286], gi\|22935... RF1_VIBC3 - Peptide chain release factor 1 OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 3... gi\|229513825, gi... - gi\|229513825\|ref\|ZP_04403287.1\| peptide chain release factor 1 [Vibrio cholerae TMA 21], gi\|22934900... gi\|229519157, gi... - gi\|229519157\|ref\|ZP_04408600.1\| peptide chain release factor 1 [Vibrio cholerae RC9], gi\|229343846\|g... gi\|229522130, gi... - gi\|229522130\|ref\|ZP_04411547.1\| peptide chain release factor 1 [Vibrio cholerae TM 11079-80], gi\|229... gi\|229337756, gi... - gi\|229524175\|ref\|ZP_04413580.1\| peptide chain release factor 1 [Vibrio cholerae bv. albensis VL426],... gi\|229332588, gi... - gi\|229528814\|ref\|ZP_04418204.1\| peptide chain release factor 1 [Vibrio cholerae 12129(1)], gi\|229332... gi\|229369943, gi... - gi\|229607288\|ref\|YP_002877936.1\| peptide chain release factor 1 [Vibrio cholerae MJ-1236], gi\|229369... gi\|197751315, gi... - gi\|254291410\|ref\|ZP_04962203.1\| peptide chain release factor 1 [Vibrio cholerae AM-19226], gi\|197751... gi\|148875897, gi... - gi\|153828626\|ref\|ZP_01981293.1\| peptide chain release factor 1 [Vibrio cholerae 623-39], gi\|14887589... gi\|149740734, gi... - gi\|153825583\|ref\|ZP_01978250.1\| peptide chain release factor 1 [Vibrio cholerae MZO-2], gi\|149740734... RF1_VIBCH - Peptide chain release factor 1 OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N169... gi\|124116034, gi... - gi\|153213234\|ref\|ZP_01948646.1\| peptide chain release factor 1 [Vibrio cholerae 1587], gi\|124116034\|... gi\|153223504, gi... - gi\|153223504\|ref\|ZP_01953906.1\| peptide chain release factor 1 [Vibrio cholerae MAK 757], gi\|1241181... gi\|124122826, gi... - gi\|153801649\|ref\|ZP_01956235.1\| peptide chain release factor 1 [Vibrio cholerae MZO-3], gi\|124122826... RF1_VIBCH - Peptide chain release factor 1 OS=Vibrio cholerae GN=prfA PE=3 SV=1 gi\|153818801, gi... - gi\|153818801\|ref\|ZP_01971468.1\| peptide chain release factor 1 [Vibrio cholerae NCTC 8457], gi\|12651... gi\|126518907, gi... - gi\|229512021\|ref\|ZP_04401500.1\| peptide chain release factor 1 [Vibrio cholerae B33], gi\|229351986\|g...	459.0	[0..33]	[393..1]

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Predicted Domain #1

Region A:
Residues: [1-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLTKKVLWY FRHGIEYQIR SIACKKGYSE HNVSRVLIEK ARSLSSEYLQ FHQVNNKDQS  60
   61 AMTNDTDLAK RIARLRRVHN AYSKFKSLSE QISDLKQMEA QESDAEVKMM AVTEINEISN 120
  121 KIPKSIEDLE NTLLPQADSY ALPALIEIRP GVGGTEAAIF ANELVEMYFQ YANFKGWNCK 180
  181 FISKSAVQGL EAITEAIFSI EGEGAYGHLM LEGGVHRVQR TPATETKGRV HTSTASVIVL 240
  241 PQVSNDESSS LYDSSEVKIE VMRSRGAGGQ HVNRTESAVR LTHIPTGITV SMQDSRSQHQ 300
  301 NKEKAFLVLN SRLAALNAAK ENEAERLKRK NQVTSSDRSE KLRTYNFNQN RVTDHRIGLS 360
  361 MHDLSTFMQG EEKFDEFLEK IRIWNREQLL LHSEIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	125.0
Match:	2b3tB
Description:	Molecular basis for bacterial class 1 release factor methylation by PrmC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation release factor activity	8.49824253851587	bayes_pls_golite062009
translation termination factor activity	8.4944923601206	bayes_pls_golite062009
translation regulator activity	5.08132283479856	bayes_pls_golite062009
translation factor activity, nucleic acid binding	5.06589285641735	bayes_pls_golite062009
nucleic acid binding	4.35723700591238	bayes_pls_golite062009
binding	3.84101343221316	bayes_pls_golite062009
translation release factor activity, codon specific	0.183484956864194	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: