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View Structure Prediction Details

Protein: res1
Organism: Schizosaccharomyces pombe
Length: 637 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for res1.

Description E-value Query
Range
Subject
Range
gi|73952670 - gi|73952670|ref|XP_536358.2| PREDICTED: similar to ankyrin 3 isoform 1 isoform 1 [Canis familiaris]
403.0 [0..3] [558..76]
gi|57162615, gi|... - gi|57209239|emb|CAI41373.1| ankyrin 3, node of Ranvier (ankyrin G) [Homo sapiens], gi|57162615|emb|C...
400.0 [0..3] [558..76]
gi|109075425 - gi|109075425|ref|XP_001095471.1| PREDICTED: ankyrin 2, neuronal isoform 12 [Macaca mulatta]
398.0 [0..3] [631..66]

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Predicted Domain #1
Region A:
Residues: [1-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNDQIHKIT YSGVEVFEYT INGFPLMKRC HDNWLNATQI LKIAELDKPR RTRILEKFAQ  60
   61 KGLHEKIQGG CGKYQGTWVP SERAVELAHE YNVFDLIQPL IEYSGSAFMP MSTFTPQSNR 120
  121 KPTEAYRRNS PVKKSFSRPS HSLLYPYTSS NNMTSTSRMS GIHDALSLQS DFTRSPDMPS 180
  181 DSFTGSLHDI KASPFSSNNY AQSLLDYFLL PNTTQPPDFV YDRPSDWDVN AGIDEDGHTA 240
  241 LHWAAAMGNL EMMHALLQAG ANVVAVNYLQ QTSLMRCVMF TMNYDLQTFE VVSELLQSAI 300
  301 CMNDSFGQTV FHHIALLASS KSKMEAARYY MDILLQNLTA TQSVDVAAQI INLQDDHGDT 360
  361 ALLICARNGA KKCARLLLSF YASSSIPNNQ GQYPTDFLSS KDMSFPENDD SPLNSKIEDN 420
  421 LIDNLKYPQS LDDHLSSKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
transcription activator activity 1.6418915400902 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
sequence-specific DNA binding 0.949906091645366 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 0.68541709976608 bayes_pls_golite062009
protein kinase regulator activity 0.576422771673579 bayes_pls_golite062009
cytoskeletal protein binding 0.56201598804914 bayes_pls_golite062009
kinase regulator activity 0.4228431685549 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [440-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PISYFSNKLT HQTLPNVFTQ LSELSKCHEA SLAEKQLTYN LAMEALEQTV RETETCQRLW  60
   61 NERTNNDENY LVNQREDLIH QCKKFLHTLK TARYYLETVQ LHQLKKYVTY FSQIWSTDEL 120
  121 ADISETKNLV GHDTKTNRSS LSSKHEVDLF TAENEAAREK LVEQLCSLQA QRKQKINEIL 180
  181 NLLSMGMYNT INTDQSGS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.979
Match: 1deqB
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle