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View Structure Prediction Details

Protein: ura4
Organism: Schizosaccharomyces pombe
Length: 264 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ura4.

Description E-value Query
Range		 Subject
Range
PYRF_PHYBL - Orotidine 5'-phosphate decarboxylase OS=Phycomyces blakesleeanus GN=pyrG PE=3 SV=1
PYRF_PHYB8 - Orotidine 5'-phosphate decarboxylase OS=Phycomyces blakesleeanus (strain ATCC 8743b / FGSC 10004 / N...
 298.0 [0..1] [264..1]
gi|82581287 - gi|82581287|dbj|BAA75262.2| orotidine-5'-phosphate decarboxylase [Candida tropicalis]
 295.0 [0..5] [263..3]
PYRF_CANMA - Orotidine 5'-phosphate decarboxylase OS=Candida maltosa GN=URA3 PE=3 SV=1
 295.0 [0..5] [263..3]
PYRF_CANDC - Orotidine 5'-phosphate decarboxylase OS=Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 ...
PYRF_CANDU - Orotidine 5'-phosphate decarboxylase OS=Candida dubliniensis GN=URA3 PE=3 SV=1
 294.0 [0..1] [263..1]
gi|156254840 - gi|156254840|gb|ABU62832.1| orotidine-5'-monophosphate decarboxylase [Expression vector pPZ3TA]
PYRF_CANAL - Orotidine 5'-phosphate decarboxylase OS=Candida albicans GN=URA3 PE=3 SV=3
PYRF_CANAL - Orotidine 5'-phosphate decarboxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=URA3 PE=...
 294.0 [0..1] [263..1]
PYRF_TORDE - Orotidine 5'-phosphate decarboxylase OS=Torulaspora delbrueckii GN=URA3 PE=3 SV=1
 293.0 [0..5] [262..2]
PYRF_CANAL - Orotidine 5'-phosphate decarboxylase OS=Candida albicans GN=URA3 PE=3 SV=2
gi|238880567 - gi|238880567|gb|EEQ44205.1| orotidine 5'-phosphate decarboxylase [Candida albicans WO-1]
 293.0 [0..1] [263..1]
PYRF_CYBJA - Orotidine 5'-phosphate decarboxylase OS=Cyberlindnera jadinii GN=URA3 PE=3 SV=1
 292.0 [0..5] [260..3]
PYRF_CYBFA - Orotidine 5'-phosphate decarboxylase OS=Cyberlindnera fabianii GN=URA3 PE=3 SV=1
 291.0 [0..5] [262..3]

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Predicted Domain #1
Region A:
Residues: [1-264] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDARVFQSYS ARAEGMKNPI AKELLALMEE KQSNLSVAVD LTKKSEILEL VDKIGPYVCV  60
   61 IKTHIDVVED FDQDMVEKLV ALGKKHRFLI FEDRKFADIG NTVKLQYASG VYKIASWAHI 120
  121 TNCHTVPGEG IIQGLKEVGL PLGRGLLLLA EMSSKGSLAT GSYTEKTLEW FEKHTDFCFG 180
  181 FIAGRRFPNL QSDYITMSPG IGLDVKGDGL GQQYRTPEEV IVNCGSDIII VGRGVYGAGR 240
  241 NPVVEAKRYR EAGWKAYQQR LSQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.69897
Match: 1dqwA
Description: Orotidine 5'-monophosphate decarboxylase (OMP decarboxylase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
orotidine-5'-phosphate decarboxylase activity 2.87717797280068 bayes_pls_golite062009
catalytic activity 2.44231061702877 bayes_pls_golite062009
binding 1.26628194990205 bayes_pls_golite062009
ribulose-phosphate 3-epimerase activity 0.982517927791965 bayes_pls_golite062009
carboxy-lyase activity 0.83446736141993 bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity 0.700596444201789 bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity 0.644387926981014 bayes_pls_golite062009
tryptophan synthase activity 0.580372404365274 bayes_pls_golite062009
carbon-carbon lyase activity 0.54291459543716 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.108467338662618 bayes_pls_golite062009
protein binding 0.014429239696785 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle