YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC11C11.10
Organism:	Schizosaccharomyces pombe
Length:	407 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC11C11.10.

Description	E-value	Query Range	Subject Range
gi\|85102286 - gi\|85102286\|ref\|XP_961309.1\| hypothetical protein NCU04153 [Neurospora crassa OR74A] gi\|28922852, gi\|... - gi\|32405760\|ref\|XP_323493.1\| related to pseudouridine synthase [MIPS] [Neurospora crassa], gi\|289228...	311.0	[0..48]	[404..6]
gi\|6179671 - gi\|6179671\|emb\|CAA18302.2\| SPBC11C11.10 [Schizosaccharomyces pombe]	307.0	[0..70]	[407..1]
gi\|145010249, gi... - gi\|39947759\|ref\|XP_363042.1\| hypothetical protein MGG_08626 [Magnaporthe grisea 70-15], gb\|EAA51104....	297.0	[0..49]	[397..9]
gi\|40746094, gi\|... - gi\|67515581\|ref\|XP_657676.1\| hypothetical protein AN0072.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	292.0	[0..46]	[403..4]
gi\|42554716, gi\|... - gi\|46125897\|ref\|XP_387502.1\| hypothetical protein FG07326.1 [Gibberella zeae PH-1], gi\|42554716\|gb\|E...	290.0	[0..48]	[403..6]
gi\|159126851 - gi\|159126851\|gb\|EDP51967.1\| pseudouridine synthase [Aspergillus fumigatus A1163] gi\|66851057, gi\|... - gi\|70997345\|ref\|XP_753421.1\| pseudouridine synthase [Aspergillus fumigatus Af293], gi\|66851057\|gb\|EA...	281.0	[0..46]	[403..4]
gi\|90298420, gi\|... - gi\|90298420\|gb\|EAS28051.1\| hypothetical protein CIMG_09255 [Coccidioides immitis RS], gi\|119174546\|r...	278.0	[0..46]	[403..1]
gi\|115387435, gi... - gi\|115387435\|ref\|XP_001211223.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	277.0	[0..46]	[406..4]
gi\|46098825, gi\|... - gi\|71017947\|ref\|XP_759204.1\| hypothetical protein UM03057.1 [Ustilago maydis 521], ref\|XP_400672.1\| ...	274.0	[0..47]	[395..59]
gi\|169779211 - gi\|169779211\|ref\|XP_001824070.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83772809 - gi\|83772809\|dbj\|BAE62937.1\| unnamed protein product [Aspergillus oryzae] gi\|220692905, gi... - gi\|238499835\|ref\|XP_002381152.1\| pseudouridine synthase [Aspergillus flavus NRRL3357], gi\|220692905\|...	270.0	[0..46]	[403..4]

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Predicted Domain #1

Region A:
Residues: [1-288]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTNTYNPT LFFTRVVFQR ITKFTAKANE ENEILFYALF VADLCLDMKG GLIAINKPSG  60
   61 RTSAQCLNEL KKIISNSELA QYFRPAPPHP NDRNRRRRKS NRLPDIKIGH GGTLDPLASG 120
  121 VLVVGLGTGT KQLSSLLSCM KTYRATALFG CSTDTYDSAG KIIKIAVHIP TKEEILSGLD 180
  181 AFRGDISQLP PLYSALHIQG KRLYEYAREG IPLPESIKAR SMHCEELILK DFIPKEEHTY 240
  241 TDPDEFASKE AIESEELLRP IEGGAERHDL LAKTEQDINP QDGDEKIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.39794
Match:	1r3fA
Description:	Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pseudouridine synthase activity	5.19957135839682	bayes_pls_golite062009
intramolecular transferase activity	3.78688422405974	bayes_pls_golite062009
isomerase activity	2.91720316078381	bayes_pls_golite062009
catalytic activity	2.02180970970004	bayes_pls_golite062009
transcription regulator activity	1.21173188039059	bayes_pls_golite062009
DNA binding	0.950713703876672	bayes_pls_golite062009
nucleic acid binding	0.909704702595901	bayes_pls_golite062009
binding	0.730744558777463	bayes_pls_golite062009
RNA binding	0.706879359688019	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [289-407]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKSPTTNSVT DVAKDQTVTN PKKRKFEVTD LARGSRPAIG PIAVLDMTVS SGFYVRSLIH  60
   61 DLGRQVNSEA HMVDLVRLKQ GSFALDDENC FDFSEFSAPG WEEKLAAAFK IDLKGDETS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.92
Match:	1k8wA
Description:	Pseudouridine synthase II TruB, C-terminal domain; Pseudouridine synthase II TruB
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: