YRC Public Data Repository - Protein Structure Prediction

Protein:	ade4
Organism:	Schizosaccharomyces pombe
Length:	533 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ade4.

Description	E-value	Query Range	Subject Range
PUR1_PASMU - Amidophosphoribosyltransferase OS=Pasteurella multocida (strain Pm70) GN=purF PE=3 SV=3 PUR1_PASMU - Amidophosphoribosyltransferase OS=Pasteurella multocida GN=purF PE=3 SV=3	420.0	[0..1]	[524..1]
gi\|7716501 - gi\|7716501\|gb\|AAF68406.1\|AF237920_1 amidophosphoribosyltransferase [Pasteurella multocida]	419.0	[0..1]	[524..1]
gi\|90579287, gi\|... - gi\|90579287\|ref\|ZP_01235097.1\| amidophosphoribosyltransferase [Vibrio angustum S14], gi\|90440120\|gb\|...	414.0	[0..1]	[524..1]
gi\|32035795 - gi\|32035795\|ref\|ZP_00135644.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Acti... gi\|190149718, gi... - gi\|190149718\|ref\|YP_001968243.1\| amidophosphoribosyltransferase [Actinobacillus pleuropneumoniae ser... gi\|126096701, gi... - gi\|126207909\|ref\|YP_001053134.1\| amidophosphoribosyltransferase [Actinobacillus pleuropneumoniae L20...	414.0	[0..1]	[524..1]
PUR1_HAEIN - Amidophosphoribosyltransferase OS=Haemophilus influenzae GN=purF PE=3 SV=2 PUR1_HAEIN - Amidophosphoribosyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)...	411.0	[0..1]	[524..1]
gi\|53732452 - gi\|53732452\|ref\|ZP_00154387.2\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Haem...	410.0	[0..1]	[524..1]
gi\|213852683 - gi\|213852683\|ref\|ZP_03382215.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|16761287 - gi\|16761287\|ref\|NP_456904.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|213426983 - gi\|213426983\|ref\|ZP_03359733.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213161329 - gi\|213161329\|ref\|ZP_03347039.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213646795 - gi\|213646795\|ref\|ZP_03376848.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|213582920 - gi\|213582920\|ref\|ZP_03364746.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|25286956, gi\|... - gi\|25286956\|pir\|\|AH0801 amidophosphoribosyltransferase (EC 2.4.2.14) [imported] - Salmonella enteric... gi\|29141017, gi\|... - gi\|29141017\|ref\|NP_804359.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser...	409.0	[0..1]	[524..1]
gi\|224583149, gi... - gi\|224583149\|ref\|YP_002636947.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|206709583, gi... - gi\|207857780\|ref\|YP_002244431.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205273256, gi... - gi\|205353475\|ref\|YP_002227276.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|204321519, gi... - gi\|204928975\|ref\|ZP_03220118.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|199605838, gi... - gi\|200388740\|ref\|ZP_03215352.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|198242494, gi... - gi\|198242494\|ref\|YP_002216435.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197361675, gi... - gi\|197361675\|ref\|YP_002141311.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|197262622, gi... - gi\|197262622\|ref\|ZP_03162696.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|197212987, gi... - gi\|197249284\|ref\|YP_002147323.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|62128567, gi\|... - gi\|62180934\|ref\|YP_217351.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194734420, gi... - gi\|194734420\|ref\|YP_002115433.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|194471463, gi... - gi\|194471463\|ref\|ZP_03077447.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ... gi\|194409186, gi... - gi\|194450882\|ref\|YP_002046418.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|56126998, gi\|... - gi\|56412741\|ref\|YP_149816.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|194444570, gi... - gi\|194444570\|ref\|YP_002041626.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|205344727, gi... - gi\|205344727\|gb\|EDZ31491.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168465927, gi... - gi\|195631420\|gb\|EDX49980.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205349326, gi... - gi\|205349326\|gb\|EDZ35957.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|205338382, gi... - gi\|205338382\|gb\|EDZ25146.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|197289640, gi... - gi\|197289640\|gb\|EDY29003.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|168229738, gi... - gi\|205335611\|gb\|EDZ22375.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|161612903, gi... - gi\|161612903\|ref\|YP_001586868.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica... gi\|238912359 - gi\|238912359\|ref\|ZP_04656196.1\| amidophosphoribosyltransferase [Salmonella enterica subsp. enterica ...	409.0	[0..1]	[524..1]
gi\|23467281, gi\|... - gi\|23467281\|ref\|ZP_00122864.1\| COG0034: Glutamine phosphoribosylpyrophosphate amidotransferase [Haem...	409.0	[0..1]	[525..1]
gi\|89073221, gi\|... - gi\|89073221\|ref\|ZP_01159751.1\| amidophosphoribosyltransferase [Photobacterium sp. SKA34], gi\|8905093...	409.0	[0..1]	[524..1]

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Predicted Domain #1

Region A:
Residues: [1-533]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGILALMLA DPHQQACPEI YEGLYSLQHR GQDAAGIVTA GNKGRLYQCK GSGMVADVFS  60
   61 QHQLRQLVGS MGIGHLRYPT AGSCAHSEAQ PFYVNSPYGL VLGHNGNLIN GPELRRFLDT 120
  121 EAHRHVNTGS DSELLLNIFA YELQRLDKFR INENDIFEAL RNVYDRVNGG YACVAMIAGL 180
  181 GVLGFRDPNG IRPLVIGERD TPEGKDYMLA SESVVLTQFG YRTFRDIRPG ECVFIRRSNR 240
  241 EDILAGFRGP RLFSRQILPC LRFTPDIFEY VYFARPDSVI DGLSVYQSRL NMGEKLAHTI 300
  301 MKRFGPDYME KIDAVIPVPD SARTSALALA QTAQLPYVEA FIKNRYIGRT FIMPGQQIRR 360
  361 KSVRRKLNVQ PQEFFDKNVL IVDDSIVRGT TSREIVQMAR ESGAKNVYLA SCAPMITHPH 420
  421 VYGIDLADCK DLIAYGKTED EVAEAISADG VIYQTLEDLL DSCRTAELTE FEVGLFTGEY 480
  481 TTGASKEYLV HLEQMRIANN RARKHSFAED EEREAPEDIS LHNTHSDVTF DFV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	113.0
Match:	1ecbA
Description:	Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	0.985266832225609	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	0.625087274084001	bayes_pls_golite062009
nucleic acid binding	0.283725923623827	bayes_pls_golite062009
ligase activity	0.204093345072151	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009
endopeptidase activity	0.0940838340168359	bayes_pls_golite062009
peptidase activity	0.0898497842822991	bayes_pls_golite062009
transcription regulator activity	0.057753538747651	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.012663147802059	bayes_pls_golite062009
protein binding	0.00621436730716318	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: