YRC Public Data Repository - Protein Structure Prediction

Protein:	pam1
Organism:	Schizosaccharomyces pombe
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pam1.

Description	E-value	Query Range	Subject Range
gi\|49657992 - gi\|49657992\|emb\|CAG90828.1\| DEHA2G17996p [Debaryomyces hansenii] gi\|50427419, gi\|... - gi\|50427419\|ref\|XP_462322.1\| hypothetical protein DEHA0G19162g [Debaryomyces hansenii CBS767], gi\|49...	195.0	[0..3]	[225..19]
gi\|67539228, gi\|... - gi\|67539228\|ref\|XP_663388.1\| hypothetical protein AN5784.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	193.0	[0..2]	[225..27]
gi\|45200773, gi\|... - gi\|45200773\|ref\|NP_986343.1\| AGL324Wp [Ashbya gossypii ATCC 10895], gi\|44985471\|gb\|AAS54167.1\| AGL32... gi\|44985471 - gi\|44985471\|gb\|AAS54167.1\| AGL324Wp [Ashbya gossypii ATCC 10895]	191.0	[0..3]	[225..21]
gi\|49525473, gi\|... - gi\|50287473\|ref\|XP_446166.1\| unnamed protein product [Candida glabrata], gi\|49525473\|emb\|CAG59090.1\|... gi\|49525473 - gi\|49525473\|emb\|CAG59090.1\| unnamed protein product [Candida glabrata]	190.0	[0..3]	[225..19]
PSB8_CANLF - Proteasome subunit beta type-8 OS=Canis lupus familiaris GN=PSMB8 PE=1 SV=1	189.0	[0..3]	[217..62]
gi\|50308397, gi\|... - gi\|50308397\|ref\|XP_454200.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643335\|emb\|CAG9928... gi\|49643335 - gi\|49643335\|emb\|CAG99287.1\| KLLA0E05633p [Kluyveromyces lactis]	188.0	[0..3]	[225..18]
gi\|83767116 - gi\|83767116\|dbj\|BAE57255.1\| unnamed protein product [Aspergillus oryzae] gi\|169769575 - gi\|169769575\|ref\|XP_001819257.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238488110, gi... - gi\|238488110\|ref\|XP_002375293.1\| proteasome component Prs3, putative [Aspergillus flavus NRRL3357], ...	187.0	[0..2]	[225..27]
gi\|109112866 - gi\|109112866\|ref\|XP_001096870.1\| PREDICTED: proteasome (prosome, macropain) subunit, beta type, 6 is...	187.0	[0..7]	[224..28]
PSB6_MOUSE - Proteasome subunit beta type-6 OS=Mus musculus GN=Psmb6 PE=1 SV=3	187.0	[0..7]	[224..27]
gi\|85111469 - gi\|85111469\|ref\|XP_963951.1\| proteasome component PRE2 precursor [Neurospora crassa OR74A] gi\|28925704, gi\|... - gi\|32423127\|ref\|XP_332001.1\| hypothetical protein [Neurospora crassa], gi\|28925704\|gb\|EAA34715.1\| pr...	186.0	[0..10]	[217..66]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQSQFDPYV QNGGTTVAIA GDGFAILAGD TRSVNGYNIN TRFQPRVHEV GDDLVIGASG  60
   61 FEADALALVK RIQQRIDLYH DNHERKMSAQ SCACMVRTLL YGKRFFPYYV YTTVAGIDKE 120
  121 GKGEIYSFDP VGSYEREWCR AGGSAANFIT PFLDNQVNLH NQYVPGSHGK ERKPRRLLKL 180
  181 EEAMKITTDA FTSAGERHIE VGDSVLVKII TKEGVETRII PLKKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.221849
Match:	1g0uL
Description:	Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	1.18139971903068	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: