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View Structure Prediction Details

Protein: pho1
Organism: Schizosaccharomyces pombe
Length: 453 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pho1.

Description E-value Query
Range
Subject
Range
PPA2_SCHPO - Thiamine-repressible acid phosphatase pho4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
pho4 - thiamine-repressible acid phosphatase Pho4
378.0 [0..1] [453..1]
PHYB_EMENI - 3-phytase B precursor (EC 3.1.3.8) (Myo-inositol-hexaphosphate 3-phosphohydrolase B) (3 phytase B) (...
368.0 [0..1] [438..1]
PHYB_EMENI - 3-phytase B OS=Emericella nidulans GN=phyB PE=3 SV=2
PHYB_EMENI - 3-phytase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=p...
366.0 [0..1] [438..1]
PHYA_ASPNG - 3-phytase A OS=Aspergillus niger GN=phyA PE=1 SV=1
360.0 [0..1] [439..1]
gi|75863998 - gi|75863998|gb|ABA29207.1| phytase [Aspergillus awamori]
358.0 [0..1] [439..1]
gi|10732783 - gi|10732783|gb|AAG22536.1| phytase [synthetic construct]
357.0 [0..11] [439..1]

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Predicted Domain #1
Region A:
Residues: [1-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLQNLFLGF LAVVCANAQF AEFTAFDGKF DFKEHLTSRS PYHKPYFYGP SIDFPTTCKI  60
   61 KQVHTLQRHG SRNPTGGNAA FDAVGIANFQ QRLLNGSVPI DYSVSGNPLS FVPTWTPVIE 120
  121 AANADALSSS GRVELFDMGR QFYERYHELF NASTYNIYTA AQQRVVDSAL WYGYGMFGED 180
  181 VHNFTNYILV SENATAGSNS LSSYNACPAS DADDFTTPAL EAWRNVYMPP IRQRLNPYFS 240
  241 NYNLTNDDIL NLYGICSYEI ALQDYSEFCK LFNSVDFLNF EYEGDLSFSY GMGNSVKWGS 300
  301 IFGGAYANSL ANSLRSVENN TQQVFFAFTH DANIIPVETA LGFFTDNTPE NPLPTSYQVH 360
  361 SHSMKASEFV PFAGNLITEL FQCEDSKYYV RHLVNEEVFP LSDCGFGPSN TSDGMCELYA 420
  421 YLNSPVRVNG TSNGIQNFDT LCNASAVAAV YPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.522879
Match: 1qfxA
Description: Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acid phosphatase activity 4.64587359284617 bayes_pls_golite062009
phosphatase activity 1.82804953813502 bayes_pls_golite062009
hydrolase activity 1.79174542059681 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.63930771076865 bayes_pls_golite062009
catalytic activity 1.37714494241232 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.01761355562415 bayes_pls_golite062009
kinase activity 0.891791120150528 bayes_pls_golite062009
binding 0.876312809995654 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.803890819223102 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.57794482374484 bayes_pls_golite062009
intramolecular transferase activity 0.17180601190736 bayes_pls_golite062009
protein binding 0.136916442724833 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle