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View Structure Prediction Details

Protein: mis3
Organism: Schizosaccharomyces pombe
Length: 327 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mis3.

Description E-value Query
Range
Subject
Range
gi|46123651, gi|... - gi|46123651|ref|XP_386379.1| hypothetical protein FG06203.1 [Gibberella zeae PH-1], gi|42551716|gb|E...
384.0 [0..20] [327..111]
KRR1_YEAS8 - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de...
KRR1_YEAS6 - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain AWRI1631) GN=KRR1 PE=3 S...
KRR1_YEASZ - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain Zymaflore VL3) GN=KRR1 P...
KRR1_YEAS1 - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain RM11-1a) GN=KRR1 PE=3 SV...
KRR1_YEASV - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain VIN 13) GN=KRR1 PE=3 SV=...
gi|151943775 - gi|151943775|gb|EDN62075.1| conserved protein [Saccharomyces cerevisiae YJM789]
KRR1_YEAST - KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
KRR1 - Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribos...
374.0 [0..20] [327..5]
gi|50422687, gi|... - gi|50422687|ref|XP_459920.1| hypothetical protein DEHA0E14685g [Debaryomyces hansenii CBS767], gi|49...
gi|49655588 - gi|49655588|emb|CAG88162.1| DEHA2E14146p [Debaryomyces hansenii]
372.0 [0..20] [325..5]
gi|40739194, gi|... - gi|67539410|ref|XP_663479.1| hypothetical protein AN5875.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
372.0 [0..20] [317..5]
gi|31377603, gi|... - gi|31377603|ref|NP_008974.4| HIV-1 rev binding protein 2 [Homo sapiens], gi|21707899|gb|AAH33887.1| ...
372.0 [0..1] [327..1]
gi|115384518, gi... - gi|115384518|ref|XP_001208806.1| ribosomal RNA assembly protein mis3 [Aspergillus terreus NIH2624], ...
371.0 [0..20] [319..5]
gi|44985404, gi|... - gi|45199264|ref|NP_986293.1| AFR744Wp [Ashbya gossypii ATCC 10895], gi|44985404|gb|AAS54117.1| AFR74...
gi|44985404 - gi|44985404|gb|AAS54117.1| AFR744Wp [Ashbya gossypii ATCC 10895]
370.0 [0..21] [322..6]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEVESSTEN NVIVNKNKRY RRDKPWDTDD IDHWKIEPFT KDDSKESFLE ESSFATLFPK  60
   61 YREKYLR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [68-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVWPHVTRAL DKFGITCVLD LVEGSMTVKT TRKTFDPYSI LDARDLIKLL ARSVPFPQAV  60
   61 KIMQDGVACD IIKIGNILRN KERFVKRRQR LIGTNGQTLK ALELLTQCYI LVQGTTVAVM 120
  121 GGYKGLKEVR RIVEDCMHNI HPIYHIKELM IKRELAKDPT LANESWDRFL PQFKKRNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1tuaA
Description: Structural genomics, 1.5A crystal structure of a hypothetical protein APE0754 from Aeropyrum pernix
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.07437653952404 bayes_pls_golite062009
mRNA binding 4.07599584461947 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 2.8667878224392 bayes_pls_golite062009
1.56143840583911 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
protein binding 0.934192915895039 bayes_pls_golite062009
poly-pyrimidine tract binding 0.9296581376632 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
single-stranded RNA binding 0.3686746342524 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [246-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARRKPAKIRE TKEYTPFPPA QPPSKLDLEI ESGEYFLKKE EKERKKRAEK KEQQKEKKKE  60
   61 KEKERMKAFI PPEESSKKRK RD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.380 0.107 rRNA processing a.22.1 Histone-fold
View Download 0.358 0.028 rRNA processing a.24.9 alpha-catenin/vinculin
View Download 0.463 0.007 rRNA processing f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.459 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.456 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle