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View Structure Prediction Details

Protein: map1
Organism: Schizosaccharomyces pombe
Length: 398 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for map1.

Description E-value Query
Range
Subject
Range
gi|73961561 - gi|73961561|ref|XP_547534.2| PREDICTED: similar to myocyte enhancer factor 2D [Canis familiaris]
260.0 [0..18] [393..1]
gi|68533065 - gi|68533065|dbj|BAE06087.1| MEF2D variant protein [Homo sapiens]
248.0 [0..14] [393..2]
MEF2D_MOUSE, MEF... - (Q63943) Myocyte-specific enhancer factor 2D, Myocyte-specific enhancer factor 2D OS=Mus musculus GN...
gi|1363258, gi|5... - gi|545520|gb|AAB29973.1| myocyte-specific enhancer-binding factor 2; MEF2 [Mus sp.], gi|1363258|pir|...
248.0 [0..18] [393..1]
gi|114560263 - gi|114560263|ref|XP_001165500.1| PREDICTED: MADS box transcription enhancer factor 2, polypeptide D ...
248.0 [0..18] [393..1]
gi|76612351 - gi|76612351|ref|XP_887917.1| PREDICTED: similar to Myocyte-specific enhancer factor 2D isoform 3 [Bo...
247.0 [0..18] [393..1]
gi|1363259, gi|5... - gi|545522|gb|AAB29974.1| myocyte-specific enhancer-binding factor 2; MEF2 [Mus sp.], gi|1363259|pir|...
246.0 [0..18] [393..1]
gi|52138610, gi|... - gi|52138610|ref|NP_110487.2| myocyte enhancer factor 2D [Rattus norvegicus], gi|51859132|gb|AAH81790...
244.0 [0..18] [393..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDERKLSNF QIDGEKAYTG SSQGNSYLED RQKRQNTFTK RKAGIFKKAN ELALLTGSEV  60
   61 MVLVVSETGL VHTFSTPKLE NVVKSPEGQK LITESL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.045757
Match: 1mnmA
Description: MCM1 transcriptional regulator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47820295830817 bayes_pls_golite062009
DNA binding 4.34885522982729 bayes_pls_golite062009
nucleic acid binding 4.22473647889076 bayes_pls_golite062009
binding 3.73009730829487 bayes_pls_golite062009
transcription factor activity 3.68208249443337 bayes_pls_golite062009
sequence-specific DNA binding 2.65616273505159 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.72567983955215 bayes_pls_golite062009
transcription activator activity 1.38059870614713 bayes_pls_golite062009
protein binding 1.27646601063623 bayes_pls_golite062009
DNA bending activity 0.167327205417291 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [97-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INATTDQNES QASQAKQSSA QLSDSESGYP LDHEEMRISE ENGPSHIENL NFFSDIDNFS  60
   61 KTSAEEIASK LFSSVSPTHE TLQFDHGLQN LEGFQANEHP EMFADHSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [205-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFYNSNNVDI PALSMLTSQT SSSSTLNLPP EPASREVKIF PKQGKRIFSP STGIDYETTG  60
   61 QHSVNSPPST YKHRRSLNKS FATRSEPQTP RKNKIRDSLQ SSPLNFPPRD RPPLIPISRI 120
  121 AVPSTIETEE RQYRGNQKII NFYAKIFEPN SGLGTSSEGA SSSFPDVDPN LAQNGVPYYS 180
  181 LPDIDHNQFD HLRR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle