YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC2G5.02c
Organism:	Schizosaccharomyces pombe
Length:	254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC2G5.02c.

Description	E-value	Query Range	Subject Range
gi\|73972260 - gi\|73972260\|ref\|XP_532075.2\| PREDICTED: similar to casein kinase 2, beta subunit [Canis familiaris]	379.0	[0..34]	[236..91]
gi\|168985483, gi... - gi\|66347790\|emb\|CAI18393.2\| casein kinase 2, beta polypeptide [Homo sapiens], gi\|168986040\|emb\|CAQ10... ENSPTRT00000033199 - null gi\|109070470 - gi\|109070470\|ref\|XP_001112540.1\| PREDICTED: similar to casein kinase 2, beta subunit isoform 2 [Maca...	375.0	[0..34]	[236..21]
gi\|51261191 - gi\|51261191\|gb\|AAH78807.1\| Csnk2b protein [Rattus norvegicus]	373.0	[0..34]	[236..28]
tr\|G3HZG2\|G3HZG2... - Casein kinase II subunit beta OS=Cricetulus griseus GN=H671_1g2786 PE=3 SV=1 gi\|53734598 - gb\|AAH83993.1\| Unknown (protein for MGC:98116) [Xenopus laevis] CSK2B_RAT - Casein kinase II subunit beta OS=Rattus norvegicus GN=Csnk2b PE=1 SV=1 CSNK2B - casein kinase 2, beta polypeptide CSK2B_PIG - Casein kinase II subunit beta OS=Sus scrofa GN=CSNK2B PE=2 SV=1 CSK2B_RABIT - Casein kinase II subunit beta OS=Oryctolagus cuniculus GN=CSNK2B PE=2 SV=1 gi\|213688918, gi... - gi\|215983072\|ref\|NP_001135983.1\| casein kinase 2, beta polypeptide [Ovis aries], gi\|213688918\|gb\|ACJ... CSK2B_MOUSE - Casein kinase II subunit beta OS=Mus musculus GN=Csnk2b PE=1 SV=1 gi\|109070472 - gi\|109070472\|ref\|XP_001112478.1\| PREDICTED: similar to casein kinase 2, beta subunit isoform 1 [Maca... CSK2B_CHICK - Casein kinase II subunit beta OS=Gallus gallus GN=CSNK2B PE=2 SV=1 ENSPTRT00000057498 - null tr\|M3W831\|M3W831... - Casein kinase II subunit beta OS=Felis catus GN=CSNK2B PE=3 SV=1 CSK2B_BOVIN - Casein kinase II subunit beta OS=Bos taurus GN=CSNK2B PE=1 SV=1 gi\|194223340 - gi\|194223340\|ref\|XP_001917725.1\| PREDICTED: similar to casein kinase 2, beta polypeptide isoform 1 [...	372.0	[0..34]	[236..2]
CSK2B_DANRE - Casein kinase II subunit beta OS=Danio rerio GN=csnk2b PE=2 SV=1 gi\|11280586, gi\|... - gi\|7672353\|gb\|AAF66446.1\|AF133088_1 CK2 beta subunit [Cyprinus carpio], gi\|11280586\|pir\|\|JC7269 prot... gi\|223649430, gi... - gi\|223649430\|gb\|ACN11473.1\| Casein kinase II subunit beta [Salmo salar], gi\|223648390\|gb\|ACN10953.1\|...	372.0	[0..34]	[236..2]
CSK2B_XENLA - Casein kinase II subunit beta OS=Xenopus laevis GN=csnk2b PE=1 SV=1 gi\|49899997, gi\|... - gi\|89271289\|emb\|CAJ82633.1\| casein kinase 2, beta subunit [Xenopus tropicalis], gi\|52346076\|ref\|NP_0...	372.0	[0..34]	[236..2]
gi\|181155 - gi\|181155\|gb\|AAA52123.1\| casein kinase II beta subunit [Homo sapiens]	372.0	[0..34]	[236..2]
gi\|60834087 - gi\|60834087\|gb\|AAX37079.1\| casein kinase 2 beta polypeptide [synthetic construct]	371.0	[0..34]	[236..2]
gi\|113639947, gi... - gi\|78709019\|gb\|ABB47994.1\| Casein kinase II beta-4 subunit, putative, expressed [Oryza sativa (japon...	370.0	[0..13]	[229..65]

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Predicted Domain #1

Region A:
Residues: [1-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKNLIKLN HDPTVTYSTK DDADELFDDL SSSPLHENVS WISWFCSRPG REYFVEVKED  60
   61 FIEDLFNLTG LNLAVPFYNE ALDLILDRTA PDTLENFDMD VIETSAQILY GLIHQRYIIT 120
  121 RTGLHQMAEK YSMGIFGCCP RVNCCYTHVL PAGLSDIVGK MPVMLFCPNC LDLYAPSSSR 180
  181 YKNIDGSFFG ATFPHLFFES YPELNPKRSI PCGKIYQPRI YGFKVSELSK TGPRMQWLRM 240
  241 YLEDSGSDSE SESD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1jwhC
Description:	Casein kinase II beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein kinase regulator activity	4.14878012076359	bayes_pls_golite062009
kinase regulator activity	4.09603095102334	bayes_pls_golite062009
enzyme regulator activity	2.91779610785511	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.79245883940915	bayes_pls_golite062009
protein kinase activity	2.75473427458132	bayes_pls_golite062009
kinase activity	2.66515798949431	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.39333807060713	bayes_pls_golite062009
protein serine/threonine kinase activity	1.99491617326192	bayes_pls_golite062009
binding	1.85951177140712	bayes_pls_golite062009
transferase activity	1.77218599619559	bayes_pls_golite062009
protein binding	1.4657010373022	bayes_pls_golite062009
catalytic activity	0.2012862421225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: