YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: hus1
Organism: Schizosaccharomyces pombe
Length: 287 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hus1.

Description E-value Query
Range
Subject
Range
gi|73991708 - gi|73991708|ref|XP_534355.2| PREDICTED: similar to proliferating cell nuclear antigen [Canis familia...
316.0 [0..3] [287..207]
PCNA_CHICK - Proliferating cell nuclear antigen OS=Gallus gallus GN=PCNA PE=1 SV=1
298.0 [0..3] [287..2]
gi|53600 - gi|53600|emb|CAA37243.1| unnamed protein product [Mus musculus]
296.0 [0..3] [287..2]
PCNA_RAT - Proliferating cell nuclear antigen OS=Rattus norvegicus GN=Pcna PE=1 SV=1
295.0 [0..3] [287..2]
PCNA_COTJA - Proliferating cell nuclear antigen OS=Coturnix coturnix japonica GN=PCNA PE=2 SV=1
295.0 [0..3] [287..2]
PCNA_BOVIN - Proliferating cell nuclear antigen OS=Bos taurus GN=PCNA PE=2 SV=1
295.0 [0..3] [287..2]
PCNA_CRIGR - Proliferating cell nuclear antigen OS=Cricetulus griseus GN=PCNA PE=1 SV=1
294.0 [0..3] [287..2]
gi|2914387, gi|2... - gi|2914387|pdb|1AXC|E Chain E, Human Pcna, gi|2914385|pdb|1AXC|C Chain C, Human Pcna
294.0 [0..3] [287..2]

Back

Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFKTRISNL YTLTRLVQAL DKIGRFCWLR LMPETVNFVI VPDFRMTQVW SVLEVETIFE  60
   61 DYVVQSNADN VINLEVPIDN FYKALRSAAN ASDSTVRLSK KNNQPLLSLS TTWSGRAFGS 120
  121 NIVTHNIPVR VLSQSYVSVI KEPTAPEPDC HIFLPQLNFL RHVVDKYKSL SDRIIMSANM 180
  181 SGELQLSVNI PSARVSTKWK GLENPELDPS QVEDISRHPS QTRAPEEFVH MRLDSKDLVN 240
  241 MLKISSVAKR VIACFCEGHA LVLYVYITDP EDEHTAVLTY YISTYVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 1axcA
Description: Prolifirating cell nuclear antigen (PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed DNA polymerase activity 5.01426276108174 bayes_pls_golite062009
DNA polymerase activity 4.9656505576274 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 3.36414326788613 bayes_pls_golite062009
DNA polymerase processivity factor activity 3.26999202934887 bayes_pls_golite062009
nucleotidyltransferase activity 3.23598180825386 bayes_pls_golite062009
transferase activity 2.5167471642449 bayes_pls_golite062009
DNA binding 2.06316167255592 bayes_pls_golite062009
nucleic acid binding 2.02054974752473 bayes_pls_golite062009
binding 1.88302251910664 bayes_pls_golite062009
structure-specific DNA binding 0.785542777582287 bayes_pls_golite062009
mismatched DNA binding 0.552326589459571 bayes_pls_golite062009
catalytic activity 0.48077242755678 bayes_pls_golite062009
double-stranded DNA binding 0.457118392479642 bayes_pls_golite062009
protein binding 0.452894757163315 bayes_pls_golite062009
DNA insertion or deletion binding 0.366820812506101 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle