| Protein: | gap1 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 766 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gap1.
| Description | E-value | Query Range |
Subject Range |
|
|
777.0 | [0..3] | [766..1058] |
|
|
772.0 | [0..3] | [766..1126] |
|
|
762.0 | [0..3] | [766..857] |
|
|
760.0 | [0..3] | [766..877] |
|
|
755.0 | [0..3] | [766..854] |
|
|
754.0 | [0..3] | [766..833] |
|
Region A: Residues: [1-106] |
1 11 21 31 41 51
| | | | | |
1 MTKRHSGTLS SSVLPQTNRL SLLRNRESTS VLYTIDLDME SDVEDAFFHL DRELHDLKQQ 60
61 ISSQSKQNFV LERDVRYLDS KIALLIQNRM AQEEQHEFAK RLNDNY
|
| Detection Method: |  |
| Confidence: | 10.0 |
| Match: | 2uzpA |
| Description: | No description for 2uzpA was found. |
|
Region A: Residues: [107-494] |
1 11 21 31 41 51
| | | | | |
1 NAVKGSFPDD RKLQLYGALF FLLQSEPAYI ASLVRRVKLF NMDALLQIVM FNIYGNQYES 60
61 REEHLLLSLF QMVLTTEFEA TSDVLSLLRA NTPVSRMLTT YTRRGPGQAY LRSILYQCIN 120
121 DVAIHPDLQL DIHPLSVYRY LVNTGQLSPS EDDNLLTNEE VSEFPAVKNA IQERSAQLLL 180
181 LTKRFLDAVL NSIDEIPYGI RWVCKLIRNL TNRLFPSISD STICSLIGGF FFLRFVNPAI 240
241 ISPQTSMLLD SCPSDNVRKT LATIAKIIQS VANGTSSTKT HLDVSFQPML KEYEEKVHNL 300
301 LRKLGNVGDF FEALELDQYI ALSKKSLALE MTVNEIYLTH EIILENLDNL YDPDSHVHLI 360
361 LQELGEPCKS VPQEDNCLVT LPLYNRWD
|
| Detection Method: | |
| Confidence: | 67.0 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 5.23789256375467 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 5.21562004568462 | bayes_pls_golite062009 |
| small GTPase regulator activity | 4.91645234075732 | bayes_pls_golite062009 |
| GTPase activator activity | 4.81440293338491 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 4.76400460221691 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| enzyme regulator activity | 4.5322075775333 | bayes_pls_golite062009 |
| enzyme activator activity | 4.29367232260052 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 3.7534755276462 | bayes_pls_golite062009 |
| binding | 2.26769740280417 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.7749599892233 | bayes_pls_golite062009 |
| protein binding | 1.21496582666968 | bayes_pls_golite062009 |
| actin binding | 1.13416719679068 | bayes_pls_golite062009 |
| microfilament motor activity | 1.03365614225436 | bayes_pls_golite062009 |
| actin filament binding | 0.839166288425262 | bayes_pls_golite062009 |
| GTPase binding | 0.54882559587114 | bayes_pls_golite062009 |
| transcription regulator activity | 0.534597007915358 | bayes_pls_golite062009 |
| nucleic acid binding | 0.400842733744238 | bayes_pls_golite062009 |
| small GTPase binding | 0.36738560339155 | bayes_pls_golite062009 |
| DNA binding | 0.313042678225127 | bayes_pls_golite062009 |
|
Region A: Residues: [495-668] |
1 11 21 31 41 51
| | | | | |
1 SSIPDLKQNL KVTREDILYV DAKTLFIQLL RLLPSGHPAT RVPLDLPLIA DSVSSLKSMS 60
61 LMKKGIRAIE LLDELSTLRL VDKENRYEPL TSEVEKEFID LDALYERIRA ERDALQDVHR 120
121 AICDHNEYLQ TQLQIYGSYL NNARSQIKPS HSDSKGFSRG VGVVGIKPKN IKSS
|
| Detection Method: | |
| Confidence: | 35.327902 |
| Match: | PF03836.6 |
| Description: | No description for PF03836.6 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [669-766] |
1 11 21 31 41 51
| | | | | |
1 NTVKLSSQQL KKESVLLNCT IPEFNVSNTY FTFSSPSTDN FVIAVYQRGH SKVLVEVCIC 60
61 LDDVLQRRYA SNPVVDLGFL TFEANKLYHL FEQLFLRK
|
| Detection Method: | |
| Confidence: | 33.0 |
| Match: | 1x0hA |
| Description: | Solution structure of the carboxyl-terminal RGC domain in human IQGAP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 3.48313315541019 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.46216378778416 | bayes_pls_golite062009 |
| enzyme regulator activity | 2.73117303901364 | bayes_pls_golite062009 |
| binding | 2.64484246147413 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.78839270261062 | bayes_pls_golite062009 |
| actin binding | 1.74809436294937 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.52776228366828 | bayes_pls_golite062009 |
| protein binding | 1.37785152807615 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.32591250158464 | bayes_pls_golite062009 |
| GTPase activator activity | 0.945543525650563 | bayes_pls_golite062009 |
| small GTPase binding | 0.78616895231719 | bayes_pls_golite062009 |
| GTPase binding | 0.76727022636058 | bayes_pls_golite062009 |
| enzyme activator activity | 0.514378360493585 | bayes_pls_golite062009 |
| enzyme binding | 0.44096806806257 | bayes_pls_golite062009 |
| Ras GTPase binding | 0.245740027562592 | bayes_pls_golite062009 |
| calmodulin binding | 0.0745132195983638 | bayes_pls_golite062009 |
