YRC Public Data Repository - Protein Structure Prediction

Protein:	erg2
Organism:	Schizosaccharomyces pombe
Length:	219 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for erg2.

Description	E-value	Query Range	Subject Range
ERG2_NEUCR - C-8 sterol isomerase OS=Neurospora crassa GN=erg-1 PE=3 SV=2 ERG2_NEUCR - C-8 sterol isomerase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / ...	333.0	[0..4]	[219..44]
gi\|67516339, gi\|... - gi\|67516339\|ref\|XP_658055.1\| hypothetical protein AN0451.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	329.0	[0..1]	[218..1]
ERG2_MAGGR - C-8 sterol isomerase OS=Magnaporthe grisea GN=ERG2 PE=3 SV=1 ERG2_MAGO7 - C-8 sterol isomerase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=ERG2 PE=3 S...	328.0	[0..4]	[219..9]
gi\|32405766, gi\|... - gi\|32405766\|ref\|XP_323496.1\| C-8 STEROL ISOMERASE (DELTA-8--DELTA-7 STEROL ISOMERASE) [Neurospora cr... gi\|85102300 - gi\|85102300\|ref\|XP_961312.1\| C-8 STEROL ISOMERASE (DELTA-8--DELTA-7 STEROL ISOMERASE) [Neurospora cr...	321.0	[0..4]	[219..44]
gi\|42554705, gi\|... - gi\|46125875\|ref\|XP_387491.1\| hypothetical protein FG07315.1 [Gibberella zeae PH-1], gi\|42554705\|gb\|E...	318.0	[0..2]	[219..23]
gi\|114193858, gi... - gi\|115390859\|ref\|XP_001212934.1\| C-8 sterol isomerase [Aspergillus terreus NIH2624], gi\|114193858\|gb...	318.0	[0..1]	[218..1]
gi\|159130697 - gi\|159130697\|gb\|EDP55810.1\| C-8 sterol isomerase (Erg-1), putative [Aspergillus fumigatus A1163] gi\|70990744, gi\|... - gi\|70990744\|ref\|XP_750221.1\| C-8 sterol isomerase (Erg-1) [Aspergillus fumigatus Af293], gi\|66847853...	312.0	[0..6]	[219..30]
SGMR1_RAT - Sigma non-opioid intracellular receptor 1 OS=Rattus norvegicus GN=Sigmar1 PE=1 SV=1	312.0	[0..6]	[210..11]
SGMR1_MOUSE - Sigma non-opioid intracellular receptor 1 OS=Mus musculus GN=Sigmar1 PE=1 SV=1 gi\|55250512 - gb\|AAH86109.1\| Unknown (protein for MGC:98493) [Xenopus laevis]	311.0	[0..6]	[210..11]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLTKFLTVF IPFIAGLIYY IQKYHLRSFY QFDPAKLQEL SKQSIALYAN DTKALLYDLS  60
   61 DRLVAEYGDL ITPVNQDEWV HNNAGGAMGT MFILHASFSE YLIFFGTPIG TEGHSGVHMA 120
  121 DDYFTILRGR QLAASANDLE ARVYLPGDQH VHPWGHTAQY SMPSGEPCFA LELAQGWIVS 180
  181 MLPFGFMDGL FSTIDFGTLY KTVYFTAGRM LKSVLMGKF

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.959
Match:	2o1qA
Description:	No description for 2o1qA was found.

Predicted functions:

Term	Confidence	Notes
intramolecular oxidoreductase activity	1.47638758343628	bayes_pls_golite062009
binding	0.725997257480172	bayes_pls_golite062009
catalytic activity	0.403492961582325	bayes_pls_golite062009
protein binding	0.17091225823897	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: